EC Number   |
Protein Variants |
Reference |
|---|
    1.4.1.1 | D196A |
alterating cofactor specificity from NADH to NADPH, 10fold decrease in activity with NADH, 4fold increase in activity with NADPH |
742134 |
| 1.4.1.1 | D196A/L197R |
alterating cofactor specificity from NADH to NADPH, almost the same activity with NADPH as the wild-type enzyme for NADH |
742134 |
| 1.4.1.1 | D196A/L197R/N198S/R201A |
alterating cofactor specificity from NADH to NADPH, loss of activity with NADH, 5fold increase in activity with NADPH |
742134 |
| 1.4.1.1 | D196A/L197R/R201A |
alterating cofactor specificity from NADH to NADPH, loss of activity with NADH, 2fold increase in activity with NADPH |
742134 |
| 1.4.1.1 | D198A |
mutant enzyme shows higher efficiency with NADP+ as coenzyme than with NAD+ |
-, 656576 |
| 1.4.1.1 | D198G |
mutant enzyme shows higher efficiency with NADP+ as coenzyme than with NAD+ |
-, 656576 |
| 1.4.1.1 | D198L |
mutant enzyme shows higher efficiency with NADP+ as coenzyme than with NAD+ |
-, 656576 |
| 1.4.1.1 | D198R |
acts also on NADP+ |
-, 656576 |
| 1.4.1.1 | D198V |
mutant enzyme shows higher efficiency with NADP+ as coenzyme than with NAD+ |
-, 656576 |
| 1.4.1.1 | D269A |
site-directed mutagenesis |
762981 |
