EC Number   |
IC50 Value |
IC50 Value Maximum |
Inhibitor |
Reference |
|---|
   2.5.1.59 | 0.000021 |
- |
2-aryl-4-aminobenzoic acid |
IC50: 21 nM |
672535 |
| 2.5.1.59 | 0.00007 |
- |
GGTI-DU40 |
complete inhibition at 5 microM, tritium-labelled geranylgeranyl diphosphate for activity assay with lysate of trabecular mesh cells, 30°C |
708819 |
| 2.5.1.59 | 0.00017 |
- |
2-{2-[3-(1H-imidazol-4-ylmethyl)-2,4-dioxo-3,4-dihydro-2H-quinazolin-1-yl]-acetylamino}-3-phenyl-propionic acid |
IC50: 170 nM |
672535 |
| 2.5.1.59 | 0.000313 |
- |
Na-(4-[[1-(3,4-dichlorophenyl)-4-[2-(methylsulfanyl)ethyl]-3-(pyridin-3-yl)-1H-pyrazol-5-yl]oxy]butanoyl)-L-phenylalaninamide |
pH and temperature not specified in the publication |
738097 |
| 2.5.1.59 | 0.000466 |
- |
N-([(2S)-2-benzyl-4-[(4-methyl-1H-imidazol-5-yl)methyl]-3-oxopiperazin-1-yl]carbonyl)-L-leucine |
pH and temperature not specified in the publication |
738097 |
| 2.5.1.59 | 0.00058 |
- |
2-{2-[3-(1H-imidazol-4-ylmethyl)-2,4-dioxo-3,4-dihydro-2H-quinazolin-1-yl]-acetylamino}-4-methyl-pentanoic acid |
IC50: 580 nM |
672535 |
| 2.5.1.59 | 0.0006 |
- |
N-[12-([[3,4,5-tris(3-ammoniopropoxy)phenyl]carbonyl]amino)dodecanoyl]-L-cysteinyl-L-valyl-L-isoleucyl-L-leucine tris(trifluoroacetate) |
- |
686092 |
| 2.5.1.59 | 0.0006 |
- |
N-[6-(3,4,5-tris(3-amino-1-propoxy)benzoylamino)-undecylcarbonyl]-L-cysteinyl-L-valyl-L-isoleucyl-L-leucine |
- |
686092 |
| 2.5.1.59 | 0.00064 |
- |
N-[6-(3,4,5-tris(3-amino-4-phenyl-1-butoxy)benzoylamino)-undecylcarbonyl]-L-cysteinyl-L-valyl-L-isoleucyl-L-leucine |
- |
686092 |
| 2.5.1.59 | 0.00066 |
- |
N-(4-[[(3-[[(3R)-3-ammonio-4-phenylbutyl]oxy]-4,5-bis[[(3S)-3-ammonio-4-phenylbutyl]oxy]phenyl)carbonyl]amino]butanoyl)-L-cysteinyl-L-valyl-L-isoleucyl-L-leucine tris(trifluoroacetate) |
- |
686092 |
