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Results 1 - 10 of 13 > >>
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EC Number Substrates Commentary Substrates Organism Products Commentary (Products) Reversibility
Display the reaction diagram Show all sequences 2.4.1.302dTDP-6-deoxy-L-glucose + novobiocic acid - Streptomyces niveus dTDP + ? - ?
Display the reaction diagram Show all sequences 2.4.1.302dTDP-beta-L-noviose + N-(4,7-dihydroxy-8-methyl-2-oxo-2H-chromen-3-yl)-4-hydroxy-3-methylbenzamide - Streptomyces sp. dTDP + N-[7-[(6-deoxy-5-methyl-beta-D-gulopyranosyl)oxy]-4-hydroxy-8-methyl-2-oxo-2H-chromen-3-yl]-4-hydroxy-3-methylbenzamide - ?
Display the reaction diagram Show all sequences 2.4.1.302dTDP-beta-L-noviose + novobiocic acid - Streptomyces sp. dTDP + demethyldecarbamoyl novobiocin i.e. demethyldecarbamoyl novobiocin ?
Display the reaction diagram Show all sequences 2.4.1.302dTDP-beta-L-noviose + novobiocic acid - Streptomyces niveus dTDP + demethyldecarbamoyl novobiocin i.e. desmethyldescarbamoyl novobiocin ?
Display the reaction diagram Show all sequences 2.4.1.302dTDP-beta-L-noviose + novobiocic acid the enzyme is involved in the biosynthesis of the aminocoumarin antibiotic, novobiocin Streptomyces niveus dTDP + demethyldecarbamoyl novobiocin i.e. demethyldecarbamoyl novobiocin ?
Display the reaction diagram Show all sequences 2.4.1.302dTDP-beta-L-noviose + novobiocic acid no activity with TDP-L-rhamnose Streptomyces niveus dTDP + demethyldecarbamoyl novobiocin - ?
Display the reaction diagram Show all sequences 2.4.1.302dTDP-beta-L-noviose + novobiocic acid sequential bi-bi catalytic mechanism. NovM binds to both donor and acceptor substrate (novobiocic acid and dTDP-L-noviose) to form a ternary complex, during which process the noviose sugar is transferred from dTDP-L-noviose to novobiocic acid. The glycosylated product, demethyldecarbamoyl novobiocin, is subsequently released from the complex Streptomyces sp. dTDP + demethyldecarbamoyl novobiocin i.e. demethyldecarbamoyl novobiocin ?
Display the reaction diagram Show all sequences 2.4.1.302dTDP-L-4-dehydro-6-deoxy-glucose + novobiocic acid - Streptomyces niveus dTDP + ? - ?
Display the reaction diagram Show all sequences 2.4.1.302dTDP-L-noviose + 4-nitrophenol kcat/Km is 208000fold lower compared to the value for the natural substrate novobiocic acid Streptomyces niveus dTDP + ? - ?
Display the reaction diagram Show all sequences 2.4.1.302dTDP-L-noviose + 7-hydroxy-4-methylcoumarin kcat/Km is 142000fold lower compared to the value for the natural substrate novobiocic acid Streptomyces niveus dTDP + ? - ?
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