EC Number |
Source Tissue |
Reference |
---|
2.3.1.21 | 3T3-L1 cell |
CPT I and CPT II |
486577 |
2.3.1.21 | adipocyte |
- |
486560, 486577 |
2.3.1.21 | adipose tissue |
- |
657826, 703294, 735980 |
2.3.1.21 | adipose tissue |
CPT1-B |
659899 |
2.3.1.21 | astrocyte |
isoforms CPT1a and CPT2 are expressed exclusively by astrocytes |
757462 |
2.3.1.21 | brain |
- |
657826, 672836, 687793, 705248, 735980 |
2.3.1.21 | brain |
brain isoform CPT1a RNA and total protein expression are unchanged throughout post-natal development (PND0, PND7, PND14, PND21 and PND50). Acylcarnitines, generated by CPT1a, significantly increase with age and peak at PND21 in all brain regions, concurrent with the increased expression of enzymes involved in mitochondrial beta-oxidation |
757462 |
2.3.1.21 | brain |
brain isoform CPT2 RNA peaks at post-natal day 21 and remains unchanged through post-natal day 50 in all regions studied. CPT2 transcript abundance is highly developmentally regulated in the cortex, midbrain, and cerebellum, and significantly increases with age. The peak of acylcarnitine abundance in all brain regions profiled at post-natal day 21 corresponds to the maximal expression of CPT2 mRNA |
757462 |
2.3.1.21 | brain |
brain-specific enzyme |
719554 |
2.3.1.21 | brain |
brain-specific isozyme |
676866 |