EC Number |
Recommended Name |
Source Tissue |
Reference |
---|
3.1.4.39 | alkylglycerophosphoethanolamine phosphodiesterase |
central nervous system |
cancer cell line |
6, 663457 |
3.4.24.11 | neprilysin |
central nervous system |
- |
735311, 81609, 81628 |
3.1.1.7 | acetylcholinesterase |
central nervous system |
and organs controlled by |
114160 |
3.1.3.9 | glucose-6-phosphatase |
central nervous system |
- |
134923 |
3.1.4.37 | 2',3'-cyclic-nucleotide 3'-phosphodiesterase |
central nervous system |
- |
135380, 135384, 135385, 135393, 135397, 135400, 135422, 670668, 750212, 752180 |
7.2.2.13 | Na+/K+-exchanging ATPase |
central nervous system |
- |
246966, 734529 |
1.3.8.6 | glutaryl-CoA dehydrogenase (ETF) |
central nervous system |
- |
391407 |
1.5.1.20 | methylenetetrahydrofolate reductase [NAD(P)H] |
central nervous system |
all regions |
392161 |
1.8.5.1 | glutathione dehydrogenase (ascorbate) |
central nervous system |
- |
394027 |
2.4.2.38 | glycoprotein 2-beta-D-xylosyltransferase |
central nervous system |
- |
394590 |
2.7.10.1 | receptor protein-tyrosine kinase |
central nervous system |
expressed during central nervous system neurogenesis |
490136 |
2.7.10.1 | receptor protein-tyrosine kinase |
central nervous system |
expression of the Tyro 3 gene is strongly up-regulated in neurons of the neocortex, cerebellum, and hippocampus after the day of birth, during periods of active synaptogenesis, and high expression is maintained in the adult CNS |
490501 |
2.7.10.1 | receptor protein-tyrosine kinase |
central nervous system |
fetal and adult human CNS, in human leukemia, lymphoma cell lines, and a variety of human cancers derived from neuroectoderm express a truncated Ror1 receptor tyrosine kinase, lacking both extracellular and transmembrane domains |
490528 |
2.7.10.2 | non-specific protein-tyrosine kinase |
central nervous system |
- |
490663 |
2.7.11.17 | Ca2+/calmodulin-dependent protein kinase |
central nervous system |
expressed in great quantities in the central nervous system in the late embryonic stage of development |
491274 |
2.7.11.17 | Ca2+/calmodulin-dependent protein kinase |
central nervous system |
during embryogenesis, larval and pupal life, transcription of caki is restricted almost exclusively to the central nervous system |
491292 |
2.7.11.1 | non-specific serine/threonine protein kinase |
central nervous system |
- |
491839 |
2.7.10.2 | non-specific protein-tyrosine kinase |
central nervous system |
expression of the enzyme remains high in the proliferating cells of the central nervous system well after cells in the rest of the embryo have ceased dividing |
532736 |
1.1.3.8 | L-gulonolactone oxidase |
central nervous system |
- |
636311 |
2.4.1.155 | alpha-1,6-mannosyl-glycoprotein 6-beta-N-acetylglucosaminyltransferase |
central nervous system |
of the embryo |
638552 |
2.7.1.107 | diacylglycerol kinase (ATP) |
central nervous system |
DGKbeta |
640382 |
2.7.3.3 | arginine kinase |
central nervous system |
- |
642475 |
1.21.99.3 | thyroxine 5-deiodinase |
central nervous system |
isozyme type III |
644804 |
1.21.99.4 | thyroxine 5'-deiodinase |
central nervous system |
isozyme type I |
644806 |
2.7.9.3 | selenide, water dikinase |
central nervous system |
- |
645493 |
3.4.14.10 | tripeptidyl-peptidase II |
central nervous system |
- |
647146 |
3.4.19.6 | pyroglutamyl-peptidase II |
central nervous system |
- |
647288 |
3.4.21.117 | stratum corneum chymotryptic enzyme |
central nervous system |
- |
647332 |
3.4.21.118 | kallikrein 8 |
central nervous system |
high expression level |
647332 |
3.4.21.B10 | neurosin |
central nervous system |
high expression level |
647332 |
1.13.11.52 | indoleamine 2,3-dioxygenase |
central nervous system |
- |
657493 |
1.14.16.2 | tyrosine 3-monooxygenase |
central nervous system |
isoenzyme DHT1 is selectively expressed in central nervous system. DTH1 cannot perform the function of the DTH II in the hypoderm |
658824 |
2.4.3.1 | beta-galactoside alpha-(2,6)-sialyltransferase |
central nervous system |
expressed during embryonic development in a tissue- and stage-specific fashion, with elevated expression in a subset of cells within the central nervous system |
659397 |
1.8.3.2 | thiol oxidase |
central nervous system |
- |
659578 |
1.14.13.39 | nitric-oxide synthase (NADPH) |
central nervous system |
- |
659646, 686010, 743260, 764938 |
1.8.3.2 | thiol oxidase |
central nervous system |
highest enzyme expression in reticular structures, such as the basal forebrain, reticular thalamic nucleus, and reticular nuclei of the brainstem |
659912 |
2.7.1.20 | adenosine kinase |
central nervous system |
- |
661642 |
2.7.11.15 | beta-adrenergic-receptor kinase |
central nervous system |
- |
662332 |
5.6.2.1 | DNA topoisomerase |
central nervous system |
level of topo I increases from birth to maturity and decreases, more significantly in males, with senescence |
662523 |
2.7.11.22 | cyclin-dependent kinase |
central nervous system |
- |
662688, 760478 |
2.7.11.22 | cyclin-dependent kinase |
central nervous system |
primary localization of CDK5 |
662688 |
2.7.11.26 | tau-protein kinase |
central nervous system |
- |
662688, 740530 |
2.7.11.12 | cGMP-dependent protein kinase |
central nervous system |
- |
662962 |
3.2.1.1 | alpha-amylase |
central nervous system |
ventral nerve cord |
664762 |
4.2.1.22 | cystathionine beta-synthase |
central nervous system |
cystathionine beta-synthase is associated with the generation and/or differentiation of the radial glia/astrocyte lineage cells in the developing central nervous system |
664879 |
3.4.11.2 | membrane alanyl aminopeptidase |
central nervous system |
- |
665113 |
4.3.2.5 | peptidylamidoglycolate lyase |
central nervous system |
- |
666112 |
2.7.11.17 | Ca2+/calmodulin-dependent protein kinase |
central nervous system |
- |
666114, 666122, 666127 |
4.2.1.1 | carbonic anhydrase |
central nervous system |
- |
666735, 748270 |
3.6.4.6 | vesicle-fusing ATPase |
central nervous system |
mRNA for Hez-NSF is present throughout the embryonic, larval and pupal development |
667820 |
3.1.3.74 | pyridoxal phosphatase |
central nervous system |
high expression |
668100 |
3.4.17.21 | Glutamate carboxypeptidase II |
central nervous system |
- |
668106, 670363, 670817 |
3.4.24.B11 | ADAMTS1 endopeptidase |
central nervous system |
- |
668117 |
3.4.17.1 | carboxypeptidase A |
central nervous system |
- |
668122 |
3.4.14.4 | dipeptidyl-peptidase III |
central nervous system |
in larva |
668562 |
3.4.13.20 | beta-Ala-His dipeptidase |
central nervous system |
the enzyme is enriched in several specific neuronal populations in the central nervous system |
669145 |
3.5.1.15 | aspartoacylase |
central nervous system |
immunohistochemical localization analysis, high enzyme content in oligodendrocytes along with CC1, and in white matter, including the corpus callosum and the cerebellar white matter, less abundant enzyme content in grey matter, including cerebral cortex, descending neuronal fibers, and microglial cells, no enzyme in astroyctes and forebrain, overview |
669635 |
3.4.11.3 | cystinyl aminopeptidase |
central nervous system |
- |
669637 |
3.5.1.2 | glutaminase |
central nervous system |
GLS1 |
669950 |
3.4.22.41 | cathepsin F |
central nervous system |
distribution, overview |
670246 |
1.3.8.8 | long-chain acyl-CoA dehydrogenase |
central nervous system |
- |
671275, 671771 |
1.6.99.1 | NADPH dehydrogenase |
central nervous system |
- |
672837 |
2.7.11.13 | protein kinase C |
central nervous system |
- |
-, 662492, 673481 |
2.7.10.1 | receptor protein-tyrosine kinase |
central nervous system |
- |
490258, 673844, 690303 |
2.7.11.18 | myosin-light-chain kinase |
central nervous system |
- |
673994 |
1.3.1.22 | 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+) |
central nervous system |
- |
676162 |
3.4.21.35 | tissue kallikrein |
central nervous system |
KLK9 and KLK11 |
678522 |
3.4.21.118 | kallikrein 8 |
central nervous system |
- |
680086 |
3.2.1.113 | mannosyl-oligosaccharide 1,2-alpha-mannosidase |
central nervous system |
In situ hybridization shows high levels of alpha1,2-mannosidase IB |
680806 |
3.1.4.39 | alkylglycerophosphoethanolamine phosphodiesterase |
central nervous system |
high levels of expression are detected in peripheral tissues, lower expression levels are observed in the central nervous system. Autotaxin isoform alpha exhibits the lowest expression levels both in the central nervous system and peripheral tissues among the three isoforms. Tissue distribution of the three isoforms alpha, beta, and gamma |
680925 |
4.6.1.2 | guanylate cyclase |
central nervous system |
atypical sGC primarily expressed |
681233 |
3.1.4.1 | phosphodiesterase I |
central nervous system |
- |
682106 |
3.4.21.B10 | neurosin |
central nervous system |
- |
-, 682129, 731396, 752889 |
2.7.12.2 | mitogen-activated protein kinase kinase |
central nervous system |
Mkk4 transcripts confined to the central nervous system in early embryogenesis, up to embryonic day 10 |
682214 |
3.1.1.7 | acetylcholinesterase |
central nervous system |
expression analysis |
682914 |
3.4.21.26 | prolyl oligopeptidase |
central nervous system |
- |
683344 |
3.4.18.1 | cathepsin X |
central nervous system |
healthy, aging, and pathological, expression patterns of cathepsin X, overview |
683448 |
3.4.13.20 | beta-Ala-His dipeptidase |
central nervous system |
- |
683621 |
3.4.21.26 | prolyl oligopeptidase |
central nervous system |
distribution, overview |
683926 |
3.4.22.40 | bleomycin hydrolase |
central nervous system |
histological examination, increase in GFAP-positively stained astroglia observed in the brains of aged null mice compared with wild-type controls |
683931 |
1.14.14.25 | cholesterol 24-hydroxylase |
central nervous system |
almost exclusive expression of gene CYP46A1 |
684856 |
3.6.4.6 | vesicle-fusing ATPase |
central nervous system |
- |
686724 |
1.14.16.2 | tyrosine 3-monooxygenase |
central nervous system |
immunohistochemic analysis of the enzyme distribution in mesencephalon, diencephalon, and telencephalon, detailed overview |
687936 |
1.14.15.4 | steroid 11beta-monooxygenase |
central nervous system |
- |
688009 |
2.3.1.67 | 1-alkylglycerophosphocholine O-acetyltransferase |
central nervous system |
primary cultured cells of |
688161 |
2.1.1.2 | guanidinoacetate N-methyltransferase |
central nervous system |
- |
688183 |
2.1.4.1 | glycine amidinotransferase |
central nervous system |
- |
688183, 690097 |
1.14.16.4 | tryptophan 5-monooxygenase |
central nervous system |
- |
688281, 689206 |
1.14.13.9 | kynurenine 3-monooxygenase |
central nervous system |
- |
689224, 763915, 765242 |
4.2.99.18 | DNA-(apurinic or apyrimidinic site) lyase |
central nervous system |
APE1 is highly expressed in selected regions of the central nervous system |
690474 |
1.2.3.1 | aldehyde oxidase |
central nervous system |
- |
691701 |
1.2.3.1 | aldehyde oxidase |
central nervous system |
presence of the AOX1 transcript in the glial cell population of the spinal cord |
691701 |
3.4.24.56 | insulysin |
central nervous system |
- |
696530 |
3.4.22.27 | cathepsin S |
central nervous system |
- |
697041 |
3.4.17.12 | carboxypeptidase M |
central nervous system |
- |
697395 |
3.4.21.68 | t-Plasminogen activator |
central nervous system |
tPA is expressed widely in the central nervous system and is involved in mechanisms of synaptic regulation and synaptic plasticity, both during development and in the mature brain |
697441 |
3.4.14.9 | tripeptidyl-peptidase I |
central nervous system |
- |
697808 |
1.14.16.2 | tyrosine 3-monooxygenase |
central nervous system |
- |
699251 |
1.4.3.3 | D-amino-acid oxidase |
central nervous system |
DAO is restricted to the lower brainstem, cerebellum and spinal cord, decreasing levels in the midbrain, the cortex and hippocampus |
699761 |
1.4.3.3 | D-amino-acid oxidase |
central nervous system |
- |
700451, 742603 |