EC Number   |
Recommended Name |
Source Tissue |
Reference |
|---|
    1.11.1.9 | glutathione peroxidase |
carotid artery |
- |
687054 |
| 1.13.11.31 | arachidonate 12-lipoxygenase |
carotid artery |
- |
671218 |
| 2.7.1.91 | sphingosine kinase |
carotid artery |
- |
671669 |
| 2.7.11.12 | cGMP-dependent protein kinase |
carotid artery |
- |
721982 |
| 2.7.11.24 | mitogen-activated protein kinase |
carotid artery |
- |
703568 |
| 2.7.8.1 | ethanolaminephosphotransferase |
carotid artery |
CEPT1 is elevated in carotid plaque of patients with diabetes |
760955 |
| 2.7.8.2 | diacylglycerol cholinephosphotransferase |
carotid artery |
CEPT1 is elevated in carotid plaque of patients with diabetes |
760955 |
| 3.1.3.17 | [phosphorylase] phosphatase |
carotid artery |
- |
94695 |
| 3.1.3.53 | [myosin-light-chain] phosphatase |
carotid artery |
smooth muscle |
646362 |
| 3.1.4.53 | 3',5'-cyclic-AMP phosphodiesterase |
carotid artery |
PDE4 |
714638 |
| 3.3.2.10 | soluble epoxide hydrolase |
carotid artery |
- |
708238 |
| 3.4.21.20 | cathepsin G |
carotid artery |
- |
665909 |
| 3.4.21.6 | coagulation factor Xa |
carotid artery |
- |
651189 |
| 3.4.21.73 | u-Plasminogen activator |
carotid artery |
standard model of the balloon catheter injury of the carotid. Periadventitial application of recombinant uPA significantly reduces lumen size and vessel area encompassed by the external lamina both 1 and 4 days after treatment.In fallatory cells accumulate in the arterial adventitia at both 1 and 4 days after uPA treatment. Four days after injury in uPA-treated arteries, 3 proinflammatory and 2 oxidation-related genes are differentially expressed |
699876 |
| 3.4.22.15 | cathepsin L |
carotid artery |
carotid atherosclerotic lesions. Expression of lysosomal cathepsin L is significantly increased in atherosclerotic plaques with formation of the necrotic core and rupture of the cap. In those plaques, cathepsin L is associated mainly with CD68-positive macrophages, whereas significant lower levels of smooth muscle cell actin are detected. The expression of cathepsin L in these plaques is also correlated with apoptosis and the stress protein ferritin. Plaques from symptomatic patients show greater increased levels of cathepsin L than those from asymptomatic patients. Human monocyte-derived macrophages from coronary artery disease patients show significantly higher levels of cathepsin L, cellular lipids and apoptosis versus cells from matched healthy donors. 7beta-hydroxycholesterol significantly enhances cathepsin L in cells from healthy donors but not in cells from coronary artery disease patients. Macrophage apoptosis is significantly correlated with expression of cathepsin L in cell nuclei and membranes |
695965 |
| 3.4.22.56 | caspase-3 |
carotid artery |
arteriosclerotic carotid artery |
668206 |
| 3.4.24.86 | ADAM 17 endopeptidase |
carotid artery |
metalloproteases ADAM-9, ADAM-15, and ADAM-17 are upregulated in advanced human atherosclerotic lesions in samples from carotid, aortic, and femoral territories compared to samples from internal thoracic artery free of atherosclerotic plaques. ADAM-9, ADAM-15, and ADAM-17-expressing cells colocalize with CD68-positive cells of monocytic origin in the atherosclerotic plaques, in the carotid territory, cells expressing the ADAMs codistribute also with smooth muscle cells |
710868 |
| 3.5.3.18 | dimethylargininase |
carotid artery |
- |
695485 |
| 3.5.4.16 | GTP cyclohydrolase I |
carotid artery |
- |
-, 686181 |
| 5.3.99.4 | prostaglandin-I synthase |
carotid artery |
- |
701619 |
| 7.2.2.10 | P-type Ca2+ transporter |
carotid artery |
- |
734295 |
