EC Number |
Recommended Name |
Source Tissue |
Reference |
---|
1.1.1.149 | 20alpha-hydroxysteroid dehydrogenase |
astrocyte |
- |
763094 |
1.1.1.21 | aldose reductase |
astrocyte |
- |
-, 739113 |
1.1.1.213 | 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific) |
astrocyte |
high expression and activity in astrocytes of glaucomatous optic nerve head |
668392 |
1.1.1.35 | 3-hydroxyacyl-CoA dehydrogenase |
astrocyte |
activated, high level expression |
673340 |
1.1.1.357 | 3alpha-hydroxysteroid 3-dehydrogenase |
astrocyte |
- |
763094 |
1.1.1.42 | isocitrate dehydrogenase (NADP+) |
astrocyte |
- |
656588 |
1.1.1.51 | 3(or 17)beta-hydroxysteroid dehydrogenase |
astrocyte |
major site for expression |
763514 |
1.1.1.95 | phosphoglycerate dehydrogenase |
astrocyte |
- |
738901 |
1.11.1.27 | glutathione-dependent peroxiredoxin |
astrocyte |
- |
765401 |
1.11.1.9 | glutathione peroxidase |
astrocyte |
- |
685439, 686868 |
1.13.11.11 | tryptophan 2,3-dioxygenase |
astrocyte |
- |
743358 |
1.13.11.31 | arachidonate 12-lipoxygenase |
astrocyte |
- |
705902 |
1.13.11.52 | indoleamine 2,3-dioxygenase |
astrocyte |
- |
657493, 743358 |
1.13.11.6 | 3-hydroxyanthranilate 3,4-dioxygenase |
astrocyte |
- |
439372, 439373 |
1.14.13.39 | nitric-oxide synthase (NADPH) |
astrocyte |
- |
-, 693776, 699996, 764565 |
1.14.13.8 | flavin-containing monooxygenase |
astrocyte |
prepared from forebrain of 1-day old Swiss Webster mice |
440389 |
1.14.14.16 | steroid 21-monooxygenase |
astrocyte |
cultured cell |
658359 |
1.14.14.25 | cholesterol 24-hydroxylase |
astrocyte |
- |
-, 705920, 712120 |
1.14.14.25 | cholesterol 24-hydroxylase |
astrocyte |
in normal brain |
659374 |
1.14.14.25 | cholesterol 24-hydroxylase |
astrocyte |
primary |
712816 |
1.14.15.15 | cholestanetriol 26-monooxygenase |
astrocyte |
primary astrocytes express different sterol hydroxylases and are able to uptake exogenous 27-hydroxycholesterol |
705935 |
1.16.3.1 | ferroxidase |
astrocyte |
of cortex |
689209 |
1.2.1.105 | 2-oxoglutarate dehydrogenase system |
astrocyte |
- |
673870, 758628 |
1.2.1.12 | glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) |
astrocyte |
primary culture |
743688 |
1.2.1.24 | succinate-semialdehyde dehydrogenase (NAD+) |
astrocyte |
- |
763330 |
1.2.1.25 | branched-chain alpha-keto acid dehydrogenase system |
astrocyte |
- |
763513 |
1.2.1.25 | branched-chain alpha-keto acid dehydrogenase system |
astrocyte |
primary cortical astrocyte cultures |
-, 763378 |
1.2.1.36 | retinal dehydrogenase |
astrocyte |
- |
725461 |
1.21.99.3 | thyroxine 5-deiodinase |
astrocyte |
cell culture |
644801 |
1.21.99.3 | thyroxine 5-deiodinase |
astrocyte |
isozyme type III |
644801 |
1.21.99.4 | thyroxine 5'-deiodinase |
astrocyte |
- |
715743 |
1.21.99.4 | thyroxine 5'-deiodinase |
astrocyte |
cell culture |
686407 |
1.3.1.24 | biliverdin reductase |
astrocyte |
- |
673797 |
1.3.8.1 | short-chain acyl-CoA dehydrogenase |
astrocyte |
- |
713043, 725641 |
1.4.1.27 | glycine cleavage system |
astrocyte |
in rat brain, the P-protein is confined to astrocytes. The intensity of astrocyte staining varies with regions, with the strongest staining in the hippocampus, the cerebellar cortex, the Bergmann glia in the cerebellum and the Muller cells in the retina |
758982 |
1.4.1.27 | glycine cleavage system |
astrocyte |
molar ratios of P-, T-, and H-protein mRNA in cerebrocortical astrocyte culture are 5.7:1.0:2.4 |
758983 |
1.4.1.3 | glutamate dehydrogenase [NAD(P)+] |
astrocyte |
- |
762783, 763376 |
1.4.1.3 | glutamate dehydrogenase [NAD(P)+] |
astrocyte |
high GDH2 expression level |
712431 |
1.4.1.3 | glutamate dehydrogenase [NAD(P)+] |
astrocyte |
predominantly |
656871 |
1.4.3.13 | protein-lysine 6-oxidase |
astrocyte |
- |
689199 |
1.4.3.3 | D-amino-acid oxidase |
astrocyte |
- |
674360, 687746, 711720 |
1.4.3.3 | D-amino-acid oxidase |
astrocyte |
in lower brain stem and cerebellum, as well as type-1 astrocytes from cerebral cortex and the cerebellum |
712324 |
1.4.3.4 | monoamine oxidase |
astrocyte |
MAO-B elevation in mouse brain astrocytes results in Parkinsons pathology |
689716 |
1.5.1.1 | 1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase [NAD(P)H] |
astrocyte |
- |
743355 |
1.5.1.2 | pyrroline-5-carboxylate reductase |
astrocyte |
- |
743355 |
1.5.1.21 | 1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase (NADPH) |
astrocyte |
- |
743355 |
1.5.1.25 | thiomorpholine-carboxylate dehydrogenase |
astrocyte |
- |
743355 |
1.6.3.1 | NAD(P)H oxidase (H2O2-forming) |
astrocyte |
- |
672959 |
1.6.3.1 | NAD(P)H oxidase (H2O2-forming) |
astrocyte |
involvement of reactive oxygen species from NADPH oxidase in cytokine induction of secretory phospholipase A2-IIA in astrocytes |
700427 |
1.6.3.1 | NAD(P)H oxidase (H2O2-forming) |
astrocyte |
isoforms NOX2 and NOX4 |
742567 |
1.6.3.1 | NAD(P)H oxidase (H2O2-forming) |
astrocyte |
primary culture. Proliferation induced by fibrillar beta-amyloid peptide Abeta1-40 is mediated both by microglial release of TNF-alpha and by production of hydrogen peroxide by enzyme |
675531 |
1.6.5.2 | NAD(P)H dehydrogenase (quinone) |
astrocyte |
enzyme is highly upregulated in active and chronic multiple sclerosis lesions, particularly in hypertrophic astrocytes and myelin-laden macrophages |
673798 |
1.8.1.7 | glutathione-disulfide reductase |
astrocyte |
- |
-, 659860, 686856 |
1.8.5.1 | glutathione dehydrogenase (ascorbate) |
astrocyte |
perivascular |
394026 |
2.1.1.2 | guanidinoacetate N-methyltransferase |
astrocyte |
- |
688183 |
2.1.1.2 | guanidinoacetate N-methyltransferase |
astrocyte |
moderate expression levels throughout development |
757807 |
2.1.1.320 | type II protein arginine methyltransferase |
astrocyte |
- |
734170 |
2.1.1.63 | methylated-DNA-[protein]-cysteine S-methyltransferase |
astrocyte |
- |
672916 |
2.1.1.63 | methylated-DNA-[protein]-cysteine S-methyltransferase |
astrocyte |
level of AGT is much reduced in mice lacking p53 |
673219 |
2.1.1.63 | methylated-DNA-[protein]-cysteine S-methyltransferase |
astrocyte |
low activity |
485498 |
2.1.1.63 | methylated-DNA-[protein]-cysteine S-methyltransferase |
astrocyte |
MGMT gene expression is substantially lower in knockout p53 astrocytes than in wild-type p53 astrocytes |
672916 |
2.1.1.67 | thiopurine S-methyltransferase |
astrocyte |
primary cell |
720847 |
2.1.1.8 | histamine N-methyltransferase |
astrocyte |
- |
704009 |
2.1.4.1 | glycine amidinotransferase |
astrocyte |
- |
686537 |
2.1.4.1 | glycine amidinotransferase |
astrocyte |
adult brain |
690097 |
2.2.1.1 | transketolase |
astrocyte |
at the lesion border |
694176 |
2.3.1.21 | carnitine O-palmitoyltransferase |
astrocyte |
isoforms CPT1a and CPT2 are expressed exclusively by astrocytes |
757462 |
2.3.1.43 | phosphatidylcholine-sterol O-acyltransferase |
astrocyte |
- |
736889 |
2.3.1.50 | serine C-palmitoyltransferase |
astrocyte |
increased SPT enzyme activity in reactive astrocytes of the hippocampus at 2 weeks post-kainate injection |
675555 |
2.3.1.50 | serine C-palmitoyltransferase |
astrocyte |
primary rat cortical astrocytes |
-, 736885 |
2.3.1.6 | choline O-acetyltransferase |
astrocyte |
- |
737113 |
2.3.1.B41 | protein-long-chain fatty-acyl-lysine deacylase (NAD+) |
astrocyte |
- |
756691 |
2.3.2.13 | protein-glutamine gamma-glutamyltransferase |
astrocyte |
insulin-like growth factor-I, epidermal growth factor, and insulin markedly increase TG-2 expression and activity. This effect is reduced when glial cultures are primed with both dexamethasone and estradiol. The regulation of TG-2 in astrocytes is signal- and hormone dependent |
688551 |
2.3.2.2 | gamma-glutamyltransferase |
astrocyte |
- |
755785 |
2.3.2.5 | glutaminyl-peptide cyclotransferase |
astrocyte |
- |
735715 |
2.4.1.1 | glycogen phosphorylase |
astrocyte |
expression of both muscle isoform and phosphorylase BB |
672848 |
2.4.1.133 | xylosylprotein 4-beta-galactosyltransferase |
astrocyte |
in the lesion site after spinal cord injury |
704802 |
2.4.1.133 | xylosylprotein 4-beta-galactosyltransferase |
astrocyte |
primary type 2 |
703134 |
2.4.1.17 | glucuronosyltransferase |
astrocyte |
- |
721077 |
2.4.1.174 | glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase |
astrocyte |
- |
759849 |
2.4.1.214 | glycoprotein 3-alpha-L-fucosyltransferase |
astrocyte |
- |
661837 |
2.4.1.38 | beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase |
astrocyte |
- |
719592 |
2.4.1.38 | beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase |
astrocyte |
primary |
688471 |
2.4.1.90 | N-acetyllactosamine synthase |
astrocyte |
- |
757808 |
2.4.1.92 | (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase |
astrocyte |
- |
688514 |
2.4.2.3 | uridine phosphorylase |
astrocyte |
primary |
676187 |
2.4.3.8 | alpha-N-acetylneuraminate alpha-2,8-sialyltransferase |
astrocyte |
in primary neurons and astrocytes lacking GD3 synthase, amyloid beta-induced cell death and amyloid beta aggregation are inhibited |
689168 |
2.5.1.16 | spermidine synthase |
astrocyte |
- |
675523 |
2.6.1.13 | ornithine aminotransferase |
astrocyte |
- |
758876 |
2.6.1.19 | 4-aminobutyrate-2-oxoglutarate transaminase |
astrocyte |
- |
702961 |
2.6.1.42 | branched-chain-amino-acid transaminase |
astrocyte |
- |
640019, 640025 |
2.6.1.64 | glutamine-phenylpyruvate transaminase |
astrocyte |
- |
288890 |
2.6.1.7 | kynurenine-oxoglutarate transaminase |
astrocyte |
- |
759251 |
2.6.1.7 | kynurenine-oxoglutarate transaminase |
astrocyte |
astrocytes in the substantia nigra express KAT-I under normal conditions. The amount of this enzyme increases after administration of 6-hydroxydopamine |
671174 |
2.7.1.1 | hexokinase |
astrocyte |
cerebrocortical astrocytes in primary culture, prepared from the neopallium |
640248 |
2.7.1.1 | hexokinase |
astrocyte |
hexokinase I: predominant in normal brain, hexokinase II: increased in brain tumors, ethylnitrosourea-induced 36B-10 astrocytic F-344 rat brain tumor cell line |
640259 |
2.7.1.127 | inositol-trisphosphate 3-kinase |
astrocyte |
cerebral cortex astrocytes, isoform B |
640758 |
2.7.1.127 | inositol-trisphosphate 3-kinase |
astrocyte |
highest expression of recombinant isoenzyme A in astrocytes of hippocampal cultures transfected with isoenzyme A |
640760 |
2.7.1.137 | phosphatidylinositol 3-kinase |
astrocyte |
- |
-, 707930, 708599 |
2.7.1.153 | phosphatidylinositol-4,5-bisphosphate 3-kinase |
astrocyte |
- |
761163 |