EC Number |
Recommended Name |
Source Tissue |
Reference |
---|
4.6.1.2 | guanylate cyclase |
aorta |
aortic ring |
693812 |
4.6.1.2 | guanylate cyclase |
aorta |
human aortic smooth muscle cells |
693087 |
4.6.1.2 | guanylate cyclase |
aorta |
primary aortic smooth muscle cells |
691841 |
4.6.1.2 | guanylate cyclase |
aorta |
vascular wall and smooth muscle cells |
691659 |
5.3.99.4 | prostaglandin-I synthase |
aorta |
- |
3200, 37458, 37460, 37461, 37462, 37463, 37465, 37466, 37467, 37468, 37469, 37470, 37475, 37476, 37477, 37478, 37479, 37480, 37485, 660924, 681029 |
5.3.99.4 | prostaglandin-I synthase |
aorta |
atherosclerotic aorta |
701992 |
5.3.99.4 | prostaglandin-I synthase |
aorta |
normal aortic endothelium. Co-distribution of prostaglandin cyclase and cyclooxygenase COX-1, while expression of cyclooxygenase COX-2 is not detected in endothelium |
678436 |
5.3.99.4 | prostaglandin-I synthase |
aorta |
normal aortic endothelium. Co-distribution of prostaglandin cyclase and cyclooxygenase COX-1, with only minor expression of cyclooxygenase COX-2 in endothelium |
678436 |
5.3.99.4 | prostaglandin-I synthase |
aorta |
normal aortic endothelium. Prostaglandin cyclase, cyclooxygenase COX-1 and thromboxane synthase are widely distributed throughout the endothelium. There is greater co-distribution of prostacyclin synthase with isoform COX-1 compared to isoform COX-2 |
678436 |
5.3.99.4 | prostaglandin-I synthase |
aorta |
significant suppression of enzyme activity in parallel with increased superoxide and enzyme nitration in the aortas of diabetic C57BL6 mice, but less effect in diabetic mice either lacking endothelial nitric oxide synthase or overexpressing human superoxide dismutase |
679435 |
5.3.99.5 | thromboxane-A synthase |
aorta |
atherosclerotic aorta |
701992 |
5.3.99.5 | thromboxane-A synthase |
aorta |
thromboxane synthase, prostaglandin cyclase and cyclooxygenase COX-1 are widely distributed throughout normal aortic endothelium |
678436 |
5.3.99.5 | thromboxane-A synthase |
aorta |
TXAS is expressed in the atherosclerotic lesion, associated with increased inflammatory cells, in particular M2 polarized macrophages |
705219 |
5.6.1.6 | channel-conductance-controlling ATPase |
aorta |
- |
675622 |
6.2.1.3 | long-chain-fatty-acid-CoA ligase |
aorta |
highly expressed in vascular endothelium |
650399 |
6.3.4.5 | argininosuccinate synthase |
aorta |
- |
690727, 690765 |
6.3.4.5 | argininosuccinate synthase |
aorta |
endothelial cell |
662377 |
7.2.2.13 | Na+/K+-exchanging ATPase |
aorta |
- |
246966, 735119 |
7.2.2.13 | Na+/K+-exchanging ATPase |
aorta |
electrogenic Na+K+-ATPase partially contributes to the ustained hyperpolarization of endothelial cells in response to acetylcholine |
685863 |
7.2.2.8 | P-type Cu+ transporter |
aorta |
- |
-, 733703, 749535 |
7.2.2.9 | P-type Cu2+ transporter |
aorta |
- |
668543 |
7.6.2.1 | P-type phospholipid transporter |
aorta |
epithelial cells |
246839 |