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EC Number	General Information	Commentary	Reference
2.6.1.51	malfunction	critical role of AGXT deletion during HCC progression, loss of AGXT expression is correlated with a poor prognosis and differentiation of HCC. Loss of AGXT expression promotes the malignant phenotypes of HCC cell lines	759686
2.6.1.51	physiological function	role of AGXT in hepatocellular carcinoma (HCC) progression with effects of AGXT on cell cycle and apoptosis in HCC cells. The proportions of both early apoptotic and late apoptotic/necrotic cells increase as the expression of AGXT decreases	759686

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Release 2023.1 (January 2023)