EC Number   |
Expression |
Reference |
|---|
    1.15.1.1 | down |
2-[(3-iodophenyl)methylsulfanyl]-5-pyridin-4-yl-1,3,4-oxadiazole, a known protein kinase inhibitor, decreases enzyme mutant G93A-SOD1 expression in vitro and in the brain and spinal cord in vivo. Compounds 3-[1-(3-hydroxypropyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]-4-(pyrazin-2-yl)-1H-pyrrole-2,5-dione, 2-chloro-1-(4,5-dibromothiophen-2-yl)ethan-1-one, 2-bromo-1-(4-bromophenyl)ethan-1-one, 4-(5-[[(3-iodophenyl)methyl]sulfanyl]-1,3,4-oxadiazol-2-yl)pyridine, 4-(5-[[(3-methoxyphenyl)methyl]sulfanyl]-1,3,4-oxadiazol-2-yl)pyridine, 4-(5-[[(3-fluorophenyl)methyl]sulfanyl]-1,3,4-oxadiazol-2-yl)pyridine, 4-[5-([[4-(trifluoromethyl)phenyl]methyl]sulfanyl)-1,3,4-oxadiazol-2-yl]pyridine, 4-(5-[[(3-chlorophenyl)methyl]sulfanyl]-1,3,4-oxadiazol-2-yl)pyridine, 4-(5-[[(3-nitrophenyl)methyl]sulfanyl]-1,3,4-oxadiazol-2-yl)pyridine, 4-(5-[[(3-bromophenyl)methyl]sulfanyl]-1,3,4-oxadiazol-2-yl)pyridine, 4-(5-[[(4-methoxyphenyl)methyl]sulfanyl]-1,3,4-oxadiazol-2-yl)pyridine, 4-(5-[[(4-chlorophenyl)methyl]sulfanyl]-1,3,4-oxadiazol-2-yl)pyridine, 4-(5-[[(4-bromophenyl)methyl]sulfanyl]-1,3,4-oxadiazol-2-yl)pyridine, 4-(5-[[(4-iodophenyl)methyl]sulfanyl]-1,3,4-oxadiazol-2-yl)pyridine, 4-(5-[[(4-fluorophenyl)methyl]sulfanyl]-1,3,4-oxadiazol-2-yl)pyridine, 4-(5-[[(4-methylphenyl)methyl]sulfanyl]-1,3,4-oxadiazol-2-yl)pyridine, 4-(5-[[(4-nitrophenyl)methyl]sulfanyl]-1,3,4-oxadiazol-2-yl)pyridine, 4-(5-[[(4-nitrophenyl)methyl]sulfanyl]-1,3,4-oxadiazol-2-yl)pyridine suppress the enzyme expression |
744500 |
| 1.15.1.1 | down |
a decrease in mRNA levels is observed for Sod1 with osmotic stress treatment |
745093 |
| 1.15.1.1 | down |
betulinic acid, i.e. BetA, from Pulsatilla chinensis suppresses SOD2 expression by BetA-induced cAMP-response element-binding protein, i.e. CREB protein, dephosphorylation at Ser133, which subsequently prevents SOD2 transcription through the required cAMP-response element-binding protein-binding motif on the SOD2 promoter, mechanism, overview |
703644 |
| 1.15.1.1 | down |
docosahexaenoic acid inhibits enzyme transcription in cancer cells, involvement of hypoxia-inducible factor-2alpha signaling, but not of peroxisome proliferator-activated receptor alpha, overview. Suppression of SOD-1 expression by clofibrate also requires hypoxia-inducible factor-2alpha and the binding element in the SOD-1 promoter |
705805 |
| 1.15.1.1 | down |
gene sodB gene, encoding Fe-SOD, is expressed highly in logarithmic phase cells but is downregulated in stationaryphase cells, except when the medium is amended with FeCl3 suggesting that downregulation of Pseudomonas putida sodB in stationary phase cells is due to Fe2+ depletion in this phase of growth. Removal of Fe2+ by adding a Fe-chelator decreases the sodB transcript level, even in logarithmicphase cells |
744281 |
| 1.15.1.1 | down |
in Portunus trituberculatus challenged with the Hematodinium parasite, transcripts in hemocytes are decreased significantly at 3 h, and then increased significantly at 12 and 24 h, followed by significant reduction from 48 to 192 h |
744948 |
| 1.15.1.1 | down |
induced overproduction of the CyAbrB transcription factor CalA (cyanobacterial AbrBlike, Alr0946) in the cyanobacterium Nostoc sp. PCC 7120 downregulates the abundance of Fe-SOD, one of two types of SODs in strain PCC 7120. Purified recombinant CalA interacts with the promoter region of alr2938, encoding Fe-SOD, indicating a transcriptional regulation of Fe-SOD by CalA |
744281 |
| 1.15.1.1 | down |
KCN inhibits Cu,Zn-SOD expression |
716572 |
| 1.15.1.1 | down |
mtMnSOD in hepatopancreas is upregulated after Aeromonas hydrophila inoculation, whereas it is downregulated after Spiroplasma eriocheiris challenge, enzyme expression pattern, overview |
746564 |
| 1.15.1.1 | down |
salinity (50 mM NaCl) causes a decrease in activities of SOD during germination. After stress the activity increases in recovered plants. During vegetative growth, the activity of SOD is strongly enhanced and responsible for salt tolerance |
744281 |
