EC Number |
Expression |
Reference |
---|
1.1.1.51 | down |
3beta-HSD is suppressed by vitamin D, about 20% at the enzyme activity level and 60% at the mRNA level |
763514 |
1.1.1.51 | down |
estradiol negatively regulates HSD17B1 in breast cancer cell lines. Dihydrotestosterone has a primarily reductive impact on HSD17B1 expression |
762076 |
1.1.1.51 | down |
GREB1 downregulation suppresses HSD17B1 |
762076 |
1.1.1.51 | down |
miRNA-1304-3p reduces HSD17B1 expression |
762076 |
1.1.1.51 | down |
miRNA-210 and miRNA-7-5p have up- and down-regulatory effect |
762076 |
1.1.1.51 | down |
the transcriptional repressor phaR gene (phaR) locates 2290 bp upstream of the betahsd gene and might bind on a special bhsd promoter domain |
-, 740307 |
1.1.1.51 | more |
estradiol and cholesterol both cannot induce betahsd gene expression in both wild-type and mutant Comamonas testosteroni |
-, 740307 |
1.1.1.51 | more |
recombinant equine gonadotropins (reFSH and reLH) and 11-oxotestosterone (11KT) have no effects on the expression of rdh11/12-like transcripts in the testis |
761195 |
1.1.1.51 | up |
3,17beta-HSD gene expression is induced by testosterone, but not by estradiol and cholesterol |
-, 740292 |
1.1.1.51 | up |
downregulation of CX3CL1, EPHB6, and TP63 increases HSD17B1 and HSD17B2 expression |
762076 |