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EC Number
Posttranslational Modification
Commentary
Reference
2.3.1.37
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ALAS2 is hydroxylated under normoxic conditions
671812
2.3.1.37
more
two heme-binding motifs in the leader sequence, as well as one present in the N-terminus of the mature enzyme, function in vivo in the heme-regulated translocation of enzyme
660994
2.3.1.37
proteolytic modification
first 49 amino acids of enzyme pre-protein are mitochondrial targeting sequence
661895
2.3.1.37
ubiquitinylation
ALAS2 appears to be ubiquitinated as rapidly as at is produced
671812
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