EC Number |
Application |
Reference |
---|
1.14.20.1 | biotechnology |
production of beta-lactam antibiotics |
700004 |
1.14.20.1 | medicine |
antibiotic cephalosporin production |
-, 699366 |
1.14.20.1 | synthesis |
bioconversion of penicillins to cephalosporins using deacetoxycephalosporin C synthase (DAOCS) is an alternative and environmentally friendly process for production of 7-aminodeacetoxycephalosporanic acid (7-ADCA), a key intermediate of many clinically useful semisynthetic cephalosporins |
-, 745495 |
1.14.20.1 | synthesis |
enzyme produces the 7-aminodeacetoxycephalosporanic acid precursor utilized in industrial applications, optimization of enzyme activity for activity with the substrate penicillin G |
657583 |
1.14.20.1 | synthesis |
expression in Escherichia coli, overexpression as an insoluble and inactive enzyme, elaboration of refolding scheme resulting in highliy active and moderately stable enzyme |
661367 |