EC Number |
Natural Substrates |
---|
2.4.2.9 | 5-fluorouracil + 5-phospho-alpha-D-ribose 1-diphosphate |
recombinant bifunctional enzyme UK/UPRT |
2.4.2.9 | 5-fluorouracil + 5-phospho-alpha-D-ribose 1-diphosphate |
recombinant fusion enzyme in RM1 tumors of lung, spleen, heart, and prostate |
2.4.2.9 | UMP + diphosphate |
- |
2.4.2.9 | uracil + 5-phospho-alpha-D-ribose 1-diphosphate |
- |
2.4.2.9 | uracil + 5-phospho-alpha-D-ribose 1-diphosphate |
incorporation of uracil into nucleotides |
2.4.2.9 | uracil + 5-phospho-alpha-D-ribose 1-diphosphate |
pyrimidine salvage enzyme, no de novo synthesis of pyrmidines |
2.4.2.9 | uracil + 5-phospho-alpha-D-ribose 1-diphosphate |
the enzyme is involved in the uracil salvage pathway, UPRT is a major cell supplier of UMP synthesized from uracil provided by preformed nucleic acid degradation, uracil salvage and pyrimidine biosynthetic pathways, overview |
2.4.2.9 | uracil + 5-phospho-alpha-D-ribose 1-diphosphate |
the enzyme is specific for uracil |
2.4.2.9 | uridine + ATP |
the bifunctional enzyme UK/UPRT also performs the uridine kinase reaction, EC 2.7.1.48 |