EC Number |
Inhibitors |
Structure |
---|
1.1.1.149 | 1,10-phenanthroline |
50% inhibition at 0.065 mM |
|
1.1.1.149 | 1,2-naphthoquinone |
0.01 mM, 55% inhibition of enzyme in liver, 10% in kidney, 10% in lung cytosolic fraction, respectively |
|
1.1.1.149 | 1-phenylcyclopentanecarboxylic acid |
- |
|
1.1.1.149 | 16alpha-Bromoacetoxyprogesterone |
- |
|
1.1.1.149 | 17alpha-hydroxyprogesterone |
most inhibitory at pH 8.0, significant at pH 6.8 |
|
1.1.1.149 | 17beta-estradiol |
20alpha-hydroxyprogesterone analog, competitive or noncompetitive depending on variable substrate |
|
1.1.1.149 | 2',5'-adenosine bisphosphate |
competitive inhibition versus NADP+ |
|
1.1.1.149 | 2',5'-ADP |
coenzyme-competitive inhibitor |
|
1.1.1.149 | 2'-adenylic acid |
coenzyme-competitive inhibitor |
|
1.1.1.149 | 2'-phosphoadenosine diphosphoribose |
coenzyme-competitive inhibitor |
|