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Results 1 - 4 of 4
EC Number General Stability Reference
Show all pathways known for 1.13.11.11Display the word mapDisplay the reaction diagram Show all sequences 1.13.11.11high tryptophan levels stabilize the active tetrameric conformation of the enzyme through binding noncatalytic exosites, resulting in rapid catabolism of tryptophan 765688
Show all pathways known for 1.13.11.11Display the word mapDisplay the reaction diagram Show all sequences 1.13.11.11in low tryptophan, the lack of tryptophan binding in the exosites destabilizes the tetramer into inactive monomers and dimers 765688
Show all pathways known for 1.13.11.11Display the word mapDisplay the reaction diagram Show all sequences 1.13.11.11one of the most rapidly degraded liver proteins with a half-life (t1/2) of about 2.3 h, relative to an average t1/2 of about 2-3 days for total liver protein 764108
Show all pathways known for 1.13.11.11Display the word mapDisplay the reaction diagram Show all sequences 1.13.11.11the nonmetabolizable analog alpha-methyl-tryptophan stabilizes tetrameric enzyme and thereby stably reduces tryptophanemia 765688
Results 1 - 4 of 4