EC Number   |
Activating Compound |
Reference |
|---|
   2.3.1.5 | 2-mercaptoethanol |
1 mM, activation |
487113 |
| 2.3.1.5 | 5-methoxypsoralen |
i.e. 5-MOP, activates the enzyme at 50 mM and the further metabolism of the product of the enzyme catalytic reaction 2-acetylaminofluorene in the stomach and colon |
673965 |
| 2.3.1.5 | 5-methoxypsoralen |
i.e. 5-MOP, activates the enzyme at 50 mM in Colo 205 cells, inhibitory at lower dosage of 0.05-0.5 mM in Colo 205 cells and at 0.5-0.25 mM in SC-M1 cells, concentrations of 5-25 mM have no effect in Colo 205 cells |
673965 |
| 2.3.1.5 | albumin |
activation, with long-chain primary amines as substrate |
487116 |
| 2.3.1.5 | cysteine |
activation |
487113 |
| 2.3.1.5 | Dimercaptosuccinate |
1 mM, activation |
487113 |
| 2.3.1.5 | glycyrrhizic acid |
slightly activates isozyme NAT1 |
677267 |
| 2.3.1.5 | more |
no activation by EDTA or histidine |
487113 |
| 2.3.1.5 | more |
the activity of NAT1 in cell culture does not change when cells are stimulated with different concentrations of sirtuin agonist resveratrol, compared to cells in culture medium. NAT2 metabolizing capacity increases significantly when sirtuins are inhibited with nicotinamide |
755743 |
| 2.3.1.5 | more |
the activity of NAT1 in cell culture does not change when cells are stimulated with different concentrations of sirtuin agonist resveratrol, compared to cells in culture medium. No effect on NAT1 activity is observed when sirtuins are inhibited with different concentrations of nicotinamide for 24 h |
755743 |
