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EC Number Activating Compound Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.203queuine PMT1 is strongly stimulated by prior queuosine (Q) modification of the substrate tRNA. In vivo tRNA methylation levels are stimulated by growth of cells in queuine-containing medium, in vitro Pmt1 activity is enhanced on Q-containing RNA; and queuine-stimulated in vivo methylation is abrogated by the absence of the eukaryotic tRNA-guanine transglycosylase 757827
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.203queuine the addition of queuine to the growth medium increases C38 methylation from 10 to 100%, while other cytosines remain unaffected 757827
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