1.13.11.31 arachidonate 12-lipoxygenase gastric cancer cell 12-LOX overexpression 686330 1.14.11.53 mRNA N6-methyladenine demethylase gastric cancer cell - 765411 1.14.11.65 [histone H3]-dimethyl-L-lysine9 demethylase gastric cancer cell - 745752 1.14.11.66 [histone H3]-trimethyl-L-lysine9 demethylase gastric cancer cell JMJD2B expression profile in gastric cancer, overview 752645 1.14.11.69 [histone H3]-trimethyl-L-lysine36 demethylase gastric cancer cell JMJD2B expression profile in gastric cancer, overview 752645 1.14.17.3 peptidylglycine monooxygenase gastric cancer cell - 438581 1.14.19.17 sphingolipid 4-desaturase gastric cancer cell - 744686, 745511 1.14.99.66 [histone H3]-N6,N6-dimethyl-L-lysine4 FAD-dependent demethylase gastric cancer cell - 698198, 745752 1.2.1.105 2-oxoglutarate dehydrogenase system gastric cancer cell - 763003 1.3.1.1 dihydropyrimidine dehydrogenase (NAD+) gastric cancer cell - 689367 2.1.1.357 [histone H3]-lysine36 N-dimethyltransferase gastric cancer cell - 753720 2.1.1.63 methylated-DNA-[protein]-cysteine S-methyltransferase gastric cancer cell - 758122 2.3.1.48 histone acetyltransferase gastric cancer cell - 703846, 756850 2.3.2.23 E2 ubiquitin-conjugating enzyme gastric cancer cell quantitative real-time PCR enzyme expression analysis in gastric cancer cell lines, overview 760224 2.4.1.102 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase gastric cancer cell GCNT3 expression in Epstein-Barr virus (EBV)-associated gastric cancer cells and tissues is lower than in EBV-negative gastric cancer cells (EBVnGC) and tissues, and high expression is significantly associated with advanced tumor-lymph node metastasis. GCNT3 is closely related to the ERK signaling pathway and epithelial mesenchymal transition (EMT), regulating cell proliferation, migration, and invasion 760226 2.4.1.150 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase gastric cancer cell GCNT3 expression in Epstein-Barr virus (EBV)-associated gastric cancer cells and tissues is lower than in EBV-negative gastric cancer cells (EBVnGC) and tissues, and high expression is significantly associated with advanced tumor-lymph node metastasis. GCNT3 is closely related to the ERK signaling pathway and epithelial mesenchymal transition (EMT), regulating cell proliferation, migration, and invasion 760226 2.4.1.155 alpha-1,6-mannosyl-glycoprotein 6-beta-N-acetylglucosaminyltransferase gastric cancer cell - 706072 2.4.1.41 polypeptide N-acetylgalactosaminyltransferase gastric cancer cell high enzyme expression in tumoral gastric tissue displaying intestinal metaplasia, increased activity compared to normal stomach, di-glycosylates MUC5AC peptide 489192 2.4.1.69 type 1 galactoside alpha-(1,2)-fucosyltransferase gastric cancer cell down regulation of alpha1,2-fucosyltransferase activity is associated with human gastric tumorigenesis 680997 2.4.1.92 (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase gastric cancer cell - 686976 2.4.2.10 orotate phosphoribosyltransferase gastric cancer cell - 676270, 685927 2.4.2.10 orotate phosphoribosyltransferase gastric cancer cell 221 specimen, expression profile of the enzyme and its antagonist dihydropyrimidine dehydrogenase both active in 5-fluorouracil metabolism, the enzyme expression levels correlate, overview 676267 2.4.2.10 orotate phosphoribosyltransferase gastric cancer cell OPRT levels are high in well differentiated and localized gastric carcinomas and are significantly higher in gastric carcinoma tissue than in normal gastric mucosa 686922 2.4.2.3 uridine phosphorylase gastric cancer cell - 684470 2.4.2.4 thymidine phosphorylase gastric cancer cell - 684468, 684476, 688212, 689292 2.4.2.4 thymidine phosphorylase gastric cancer cell enzyme activity is higher in cancer tiddue than in adjacent normal tissue 659750 2.7.1.105 6-phosphofructo-2-kinase gastric cancer cell - 737973, 761915 2.7.1.137 phosphatidylinositol 3-kinase gastric cancer cell - 708417 2.7.1.91 sphingosine kinase gastric cancer cell - 671356 2.7.1.94 acylglycerol kinase gastric cancer cell high expression level 662505 2.7.10.1 receptor protein-tyrosine kinase gastric cancer cell - 490316, 490356, 490365, 490389, 690303 2.7.10.1 receptor protein-tyrosine kinase gastric cancer cell gastric cancer 490371 2.7.11.12 cGMP-dependent protein kinase gastric cancer cell - 760502 2.7.11.19 phosphorylase kinase gastric cancer cell - 741081 2.7.11.22 cyclin-dependent kinase gastric cancer cell mRNA levels of CDK7 are statistically overexpressed in gastric cancer cells when compared with matched normal tissues. Upregulation of cyclin-dependent kinase 7 contributes to metastatic properties of gastric cancer. High expression of MMP14 and CDK7 are independent prognostic factors for overall survival in patients with gastric cancer 761329 2.7.2.3 phosphoglycerate kinase gastric cancer cell - 761524 2.7.2.3 phosphoglycerate kinase gastric cancer cell primary gastric carcinoma, overexpression of PGK1 and its signalling targets may be a expression-pathway in diffuse primary gastric carcinomas promoting peritoneal dissemination and may function as prognostic markers and/or be potential therapeutic targets to prevent the migration of gastric carcinoma cells into the peritoneum 686031 3.1.13.4 poly(A)-specific ribonuclease gastric cancer cell poly(A)-specific ribonuclease (PARN) is upregulated in gastric tumor tissues and gastric cancer cell lines MKN28 and AGS, determination of the expression level of PARN in human gastric cancer cells and tissues by quantitative real-time PCR expression analysis 749952 3.1.3.67 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase gastric cancer cell tissue from patients with sporadic gastric carcinoma 691598 3.2.1.166 heparanase gastric cancer cell - 731867 3.4.17.21 Glutamate carboxypeptidase II gastric cancer cell PSMA is expressed in the neovasculature of multiple nonprostatic solid tumors, it shows a unique expression pattern limited to tumor-associated endothelial cells. Expression in liver metastasis from colorectal cancers and lymph node metastasis from colorectal cancers 708666 3.4.18.1 cathepsin X gastric cancer cell - 666147 3.4.21.107 peptidase Do gastric cancer cell high HtrA1 expression levels 683704 3.4.21.119 kallikrein 13 gastric cancer cell - 732961 3.4.21.46 complement factor D gastric cancer cell - 710586 3.4.21.B10 neurosin gastric cancer cell high enzyme upregulation 732962 3.4.21.B10 neurosin gastric cancer cell KLK6 is upregulated 679036 3.4.21.B28 fibroblast activation protein alpha subunit gastric cancer cell mainly located, seprase-expressing carcinoma tissue more often found in the scirrhous type than in other types of gastric carcinoma 676269 3.4.21.B41 kallikrein 10 gastric cancer cell - 681167 3.4.21.B41 kallikrein 10 gastric cancer cell significantly upregulated 670979 3.4.21.B42 hippostasin gastric cancer cell - 718041 3.4.22.1 cathepsin B gastric cancer cell of a more aggressive tumor type, cathepsin B is most common in the intestinal type tumors infiltrating the whole gastric wall 698029 3.4.22.34 Legumain gastric cancer cell legumain is overexpressed in the majority of human solid tumours, including breast cancer, colorectal cancer, ovarian cancer, prostate cancer and gastric cancer 752851 3.4.22.38 cathepsin K gastric cancer cell - 697066 3.4.22.62 caspase-9 gastric cancer cell caspase-9 mutations in the tumors are detected, the frequency of the mutations is very low and all the mutations are silent mutations that may not alter the function of the caspase protein. Caspase-9 gene mutation may not contribute to the pathogenesis of this cancer 663673 3.4.22.B29 calpain 9 gastric cancer cell suppressed or depleted in gastric cancer cell lines of differentiated and poorly differentiated types 648099 3.4.22.B72 SENP3 peptidase gastric cancer cell correlation between SENP3 expression and gastric cancer metastasis 732595 3.4.24.23 matrilysin gastric cancer cell high expression level 710651 3.4.24.23 matrilysin gastric cancer cell primary specimen, overexpression of MMP-7, realtime PCR, RT-PCR or Western blotting analysis 707870 3.4.24.35 gelatinase B gastric cancer cell - 696967, 708542 3.4.24.35 gelatinase B gastric cancer cell proteolytic activity and expression of gelatinase B in serum of gastric cancer patients and their correlation with the stage of the tumor 684107 3.4.24.61 nardilysin gastric cancer cell - 733727 3.4.24.80 membrane-type matrix metalloproteinase-1 gastric cancer cell - 638810 3.4.24.80 membrane-type matrix metalloproteinase-1 gastric cancer cell mRNA and protein levels of MMP14 are increased in gastric cancer cell. Upregulation of matrix metalloproteinase-14 expression contributes to metastatic properties of gastric cancer. MMP14 expression is related to advanced TNM stage, tumor grade, and lymph node metastasis. High expression of MMP14 and CDK7 are independent prognostic factors for overall survival in patients with gastric cancer 761331 3.4.24.86 ADAM 17 endopeptidase gastric cancer cell - 753900 3.4.24.B3 matrix metalloproteinase-11 gastric cancer cell - 708156, 708668 3.4.24.B7 matrix metalloproteinase-26 gastric cancer cell - 710794 3.4.24.B9 ADAM9 endopeptidase gastric cancer cell - 668997 3.5.1.98 histone deacetylase gastric cancer cell - 713036 3.5.4.4 adenosine deaminase gastric cancer cell - 733602 3.6.1.29 bis(5'-adenosyl)-triphosphatase gastric cancer cell - 699134 4.1.1.17 ornithine decarboxylase gastric cancer cell - 698322 4.1.1.17 ornithine decarboxylase gastric cancer cell relationship between expression level of the enzyme and mucosal proliferation, overview -, 747964 4.1.1.28 aromatic-L-amino-acid decarboxylase gastric cancer cell different splicing variants 748845 4.2.1.11 phosphopyruvate hydratase gastric cancer cell ENOA is upregulated 714970 5.1.99.4 alpha-methylacyl-CoA racemase gastric cancer cell - 728837 5.6.2.2 DNA topoisomerase (ATP-hydrolysing) gastric cancer cell primary. Topo-IIalpha expression in the gastric adenocarcinoma is positively correlated with tumor location in the gastric cardia, intestinal histological type, late age onset of gastric adenocarcinoma, and male gender, but with no other clinicopathological parameters or with survival, overview 714645 6.1.1.6 lysine-tRNA ligase gastric cancer cell high expression of KRS in tumor cells is noted in 43.3 % (198 of 457) of the cases. High expression of KRS in tumor-associated inflammatory cells including macrophages/monocytes, CD4-positive T cells, and/or neutrophils is observed in 37.2 % (170 of 457) of the cases, overview 744045 6.3.4.3 formate-tetrahydrofolate ligase gastric cancer cell - 765141 7.4.2.3 mitochondrial protein-transporting ATPase gastric cancer cell - 751766