1.1.3.8 L-gulonolactone oxidase central nervous system - 636311 1.11.1.20 prostamide/prostaglandin F2alpha synthase central nervous system prostamide/PGF synthase is expressed preferentially in the white matter bundles of the entire central nervous system of adult mice with less marked expression in neuronal cell bodies 707934 1.13.11.52 indoleamine 2,3-dioxygenase central nervous system - 657493 1.14.13.39 nitric-oxide synthase (NADPH) central nervous system - 659646, 686010, 743260, 764938 1.14.13.39 nitric-oxide synthase (NADPH) central nervous system the localization of NADPH-diaphorase and NO synthase is identical in the snail nervous system 743260 1.14.13.9 kynurenine 3-monooxygenase central nervous system - 689224, 763915, 765242 1.14.14.19 steroid 17alpha-monooxygenase central nervous system fetal 727367 1.14.14.25 cholesterol 24-hydroxylase central nervous system - -, 735602 1.14.14.25 cholesterol 24-hydroxylase central nervous system almost exclusive expression of gene CYP46A1 684856 1.14.15.15 cholestanetriol 26-monooxygenase central nervous system - 713175 1.14.15.15 cholestanetriol 26-monooxygenase central nervous system expression pattern of Cyp27a1 and other related genes in primary cultures of glia and neurons 705935 1.14.15.4 steroid 11beta-monooxygenase central nervous system - 688009 1.14.16.2 tyrosine 3-monooxygenase central nervous system - 699251 1.14.16.2 tyrosine 3-monooxygenase central nervous system immunohistochemic analysis of the enzyme distribution in mesencephalon, diencephalon, and telencephalon, detailed overview 687936 1.14.16.2 tyrosine 3-monooxygenase central nervous system isoenzyme DHT1 is selectively expressed in central nervous system. DTH1 cannot perform the function of the DTH II in the hypoderm 658824 1.14.16.4 tryptophan 5-monooxygenase central nervous system - 688281, 689206 1.15.1.1 superoxide dismutase central nervous system - 745523 1.2.3.1 aldehyde oxidase central nervous system - 691701 1.2.3.1 aldehyde oxidase central nervous system presence of the AOX1 transcript in the glial cell population of the spinal cord 691701 1.21.99.3 thyroxine 5-deiodinase central nervous system - 744614 1.21.99.3 thyroxine 5-deiodinase central nervous system isozyme type III 644804 1.21.99.4 thyroxine 5'-deiodinase central nervous system isozyme type I 644806 1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+) central nervous system - 676162 1.3.5.2 dihydroorotate dehydrogenase (quinone) central nervous system regiospecific distribution of DHODH, immunohistochemic analysis, overview 713150 1.3.8.6 glutaryl-CoA dehydrogenase (ETF) central nervous system - 391407 1.3.8.8 long-chain acyl-CoA dehydrogenase central nervous system - 671275, 671771 1.4.1.27 glycine cleavage system central nervous system - 758983 1.4.3.3 D-amino-acid oxidase central nervous system - 700451, 742603 1.4.3.3 D-amino-acid oxidase central nervous system DAO is restricted to the lower brainstem, cerebellum and spinal cord, decreasing levels in the midbrain, the cortex and hippocampus 699761 1.5.1.20 methylenetetrahydrofolate reductase [NAD(P)H] central nervous system all regions 392161 1.6.99.1 NADPH dehydrogenase central nervous system - 672837 1.8.3.2 thiol oxidase central nervous system - 659578 1.8.3.2 thiol oxidase central nervous system highest enzyme expression in reticular structures, such as the basal forebrain, reticular thalamic nucleus, and reticular nuclei of the brainstem 659912 1.8.5.1 glutathione dehydrogenase (ascorbate) central nervous system - 394027 2.1.1.2 guanidinoacetate N-methyltransferase central nervous system - 688183 2.1.1.325 juvenile hormone-III synthase central nervous system highest expression 738375 2.1.1.37 DNA (cytosine-5-)-methyltransferase central nervous system - 700956 2.1.4.1 glycine amidinotransferase central nervous system - 688183, 690097 2.3.1.299 sphingoid base N-stearoyltransferase central nervous system - 757888 2.3.1.67 1-alkylglycerophosphocholine O-acetyltransferase central nervous system primary cultured cells of 688161 2.3.2.13 protein-glutamine gamma-glutamyltransferase central nervous system the central nervous system has a tTG splice variant which is termed tTG-short, or tTG-S. tTG-S adopts a conformation similar to the open-state 759712 2.3.2.5 glutaminyl-peptide cyclotransferase central nervous system - 759702 2.3.2.8 arginyltransferase central nervous system - 758964 2.4.1.122 N-acetylgalactosaminide beta-1,3-galactosyltransferase central nervous system - 759109 2.4.1.122 N-acetylgalactosaminide beta-1,3-galactosyltransferase central nervous system during embryogenesis, in late embryos at stage 16 703884 2.4.1.122 N-acetylgalactosaminide beta-1,3-galactosyltransferase central nervous system in embryo 703369 2.4.1.155 alpha-1,6-mannosyl-glycoprotein 6-beta-N-acetylglucosaminyltransferase central nervous system of the embryo 638552 2.4.1.174 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase central nervous system - 759849 2.4.1.275 neolactotriaosylceramide beta-1,4-galactosyltransferase central nervous system - 715438 2.4.2.38 glycoprotein 2-beta-D-xylosyltransferase central nervous system - 394590 2.4.3.1 beta-galactoside alpha-(2,6)-sialyltransferase central nervous system expressed during embryonic development in a tissue- and stage-specific fashion, with elevated expression in a subset of cells within the central nervous system 659397 2.5.1.59 protein geranylgeranyltransferase type I central nervous system - -, 738895 2.6.1.42 branched-chain-amino-acid transaminase central nervous system - 721137 2.7.1.107 diacylglycerol kinase (ATP) central nervous system DGKbeta 640382 2.7.1.107 diacylglycerol kinase (ATP) central nervous system isozyme DGK-theta shows a striking predominate localization in the nervous system 737399 2.7.1.127 inositol-trisphosphate 3-kinase central nervous system - 700975, 762015 2.7.1.149 1-phosphatidylinositol-5-phosphate 4-kinase central nervous system - 738389 2.7.1.183 glycoprotein-mannosyl O6-kinase central nervous system - 762091 2.7.1.20 adenosine kinase central nervous system - 661642 2.7.10.1 receptor protein-tyrosine kinase central nervous system - 490258, 673844, 690303 2.7.10.1 receptor protein-tyrosine kinase central nervous system expressed during central nervous system neurogenesis 490136 2.7.10.1 receptor protein-tyrosine kinase central nervous system expression of the Tyro 3 gene is strongly up-regulated in neurons of the neocortex, cerebellum, and hippocampus after the day of birth, during periods of active synaptogenesis, and high expression is maintained in the adult CNS 490501 2.7.10.1 receptor protein-tyrosine kinase central nervous system fetal and adult human CNS, in human leukemia, lymphoma cell lines, and a variety of human cancers derived from neuroectoderm express a truncated Ror1 receptor tyrosine kinase, lacking both extracellular and transmembrane domains 490528 2.7.10.2 non-specific protein-tyrosine kinase central nervous system - 490663 2.7.10.2 non-specific protein-tyrosine kinase central nervous system expression of the enzyme remains high in the proliferating cells of the central nervous system well after cells in the rest of the embryo have ceased dividing 532736 2.7.11.1 non-specific serine/threonine protein kinase central nervous system - 491839 2.7.11.12 cGMP-dependent protein kinase central nervous system - 662962 2.7.11.13 protein kinase C central nervous system - -, 662492, 673481 2.7.11.15 beta-adrenergic-receptor kinase central nervous system - 662332 2.7.11.17 Ca2+/calmodulin-dependent protein kinase central nervous system - 666114, 666122, 666127 2.7.11.17 Ca2+/calmodulin-dependent protein kinase central nervous system during embryogenesis, larval and pupal life, transcription of caki is restricted almost exclusively to the central nervous system 491292 2.7.11.17 Ca2+/calmodulin-dependent protein kinase central nervous system expressed in great quantities in the central nervous system in the late embryonic stage of development 491274 2.7.11.18 myosin-light-chain kinase central nervous system - 673994 2.7.11.22 cyclin-dependent kinase central nervous system - 662688, 760478 2.7.11.22 cyclin-dependent kinase central nervous system primary localization of CDK5 662688 2.7.11.26 tau-protein kinase central nervous system - 662688, 740530 2.7.11.26 tau-protein kinase central nervous system splicing variant GSK-3beta2 740125 2.7.12.2 mitogen-activated protein kinase kinase central nervous system Mkk4 transcripts confined to the central nervous system in early embryogenesis, up to embryonic day 10 682214 2.7.3.3 arginine kinase central nervous system - 642475 2.7.7.43 N-acylneuraminate cytidylyltransferase central nervous system robust expression in the entire central nervous system, the somites, the notochord, and the developing pronephric duct 722748 2.7.9.3 selenide, water dikinase central nervous system - 645493 2.8.2.23 [heparan sulfate]-glucosamine 3-sulfotransferase 1 central nervous system - 739503 3.1.1.34 lipoprotein lipase central nervous system - -, 750657 3.1.1.53 sialate O-acetylesterase central nervous system - 750712 3.1.1.7 acetylcholinesterase central nervous system - 749734 3.1.1.7 acetylcholinesterase central nervous system and organs controlled by 114160 3.1.1.7 acetylcholinesterase central nervous system expression analysis 682914 3.1.1.7 acetylcholinesterase central nervous system isoform AChE2 is predominately expressed in the central nervous system (CNS) while isoform AChE1 is abundantly observed not only in the CNS but also in the peripheral nervous system/non-neuronal tissues 730711 3.1.1.8 cholinesterase central nervous system - 751209 3.1.1.96 D-aminoacyl-tRNA deacylase central nervous system most intense expression is observed in hippocampal pyramidal cells, cerebellar Purkinje cells and most layers of the cerebral cortex 724218 3.1.1.98 [Wnt protein] O-palmitoleoyl-L-serine hydrolase central nervous system at 24 h post fertilization, expression is particularly pronounced in the central nervous system, including the dorsal neural tube and the midbrain-hindbrain boundary 733700 3.1.26.11 tRNase Z central nervous system predominant expression during the third larval instar 729616 3.1.3.4 phosphatidate phosphatase central nervous system - 708068 3.1.3.74 pyridoxal phosphatase central nervous system high expression 668100 3.1.3.9 glucose-6-phosphatase central nervous system - 134923 3.1.3.B4 phosphatidylinositol-4-phosphate phosphatase central nervous system - 752310 3.1.4.1 phosphodiesterase I central nervous system - 682106 3.1.4.37 2',3'-cyclic-nucleotide 3'-phosphodiesterase central nervous system - 135380, 135384, 135385, 135393, 135397, 135400, 135422, 670668, 750212, 752180 3.1.4.39 alkylglycerophosphoethanolamine phosphodiesterase central nervous system cancer cell line 6, 663457 3.1.4.39 alkylglycerophosphoethanolamine phosphodiesterase central nervous system high levels of expression are detected in peripheral tissues, lower expression levels are observed in the central nervous system. Autotaxin isoform alpha exhibits the lowest expression levels both in the central nervous system and peripheral tissues among the three isoforms. Tissue distribution of the three isoforms alpha, beta, and gamma 680925 3.1.8.2 diisopropyl-fluorophosphatase central nervous system - 751626 3.2.1.1 alpha-amylase central nervous system ventral nerve cord 664762 3.2.1.113 mannosyl-oligosaccharide 1,2-alpha-mannosidase central nervous system In situ hybridization shows high levels of alpha1,2-mannosidase IB 680806 3.4.11.2 membrane alanyl aminopeptidase central nervous system - 665113 3.4.11.3 cystinyl aminopeptidase central nervous system - 669637 3.4.13.20 beta-Ala-His dipeptidase central nervous system - 683621 3.4.13.20 beta-Ala-His dipeptidase central nervous system the enzyme is enriched in several specific neuronal populations in the central nervous system 669145 3.4.14.10 tripeptidyl-peptidase II central nervous system - 647146 3.4.14.4 dipeptidyl-peptidase III central nervous system in larva 668562 3.4.14.9 tripeptidyl-peptidase I central nervous system - 697808 3.4.17.1 carboxypeptidase A central nervous system - 668122 3.4.17.12 carboxypeptidase M central nervous system - 697395 3.4.17.21 Glutamate carboxypeptidase II central nervous system - 668106, 670363, 670817 3.4.18.1 cathepsin X central nervous system healthy, aging, and pathological, expression patterns of cathepsin X, overview 683448 3.4.19.12 ubiquitinyl hydrolase 1 central nervous system - 709780 3.4.19.6 pyroglutamyl-peptidase II central nervous system - 647288 3.4.21.117 stratum corneum chymotryptic enzyme central nervous system - 647332 3.4.21.118 kallikrein 8 central nervous system - 680086 3.4.21.118 kallikrein 8 central nervous system high expression level 647332 3.4.21.26 prolyl oligopeptidase central nervous system - 683344 3.4.21.26 prolyl oligopeptidase central nervous system distribution, overview 683926 3.4.21.35 tissue kallikrein central nervous system - 731367 3.4.21.35 tissue kallikrein central nervous system KLK9 and KLK11 678522 3.4.21.61 Kexin central nervous system - 731241 3.4.21.68 t-Plasminogen activator central nervous system tissue-type plasminogen activator is a major protease of the central nervous system 718064 3.4.21.68 t-Plasminogen activator central nervous system tPA is expressed widely in the central nervous system and is involved in mechanisms of synaptic regulation and synaptic plasticity, both during development and in the mature brain 697441 3.4.21.B10 neurosin central nervous system - -, 682129, 731396, 752889 3.4.21.B10 neurosin central nervous system high expression level 647332 3.4.21.B10 neurosin central nervous system highly expressed in the central nervous system and with elevated level in demyelinating disease 752827 3.4.21.B10 neurosin central nervous system predominantly expressed in the central nervous system 710110 3.4.22.27 cathepsin S central nervous system - 697041 3.4.22.40 bleomycin hydrolase central nervous system histological examination, increase in GFAP-positively stained astroglia observed in the brains of aged null mice compared with wild-type controls 683931 3.4.22.41 cathepsin F central nervous system distribution, overview 670246 3.4.22.B25 calpain 5 central nervous system - -, 732139 3.4.22.B25 calpain 5 central nervous system CAPN5 signals are widely detected and are especially strong in the hippocampal formation and the piriform cortex 754701 3.4.22.B25 calpain 5 central nervous system high expression level -, 732139 3.4.23.B24 signal peptide peptidase central nervous system high SPPL2b expression rate 752819 3.4.24.11 neprilysin central nervous system - 735311, 81609, 81628 3.4.24.15 thimet oligopeptidase central nervous system - -, 709612, 733958 3.4.24.17 stromelysin 1 central nervous system - 709370 3.4.24.17 stromelysin 1 central nervous system age-dependent increase in the central nervous system expression of MMP-3 in Twitcher mice suffering globoid cell leukodystrophy -, 733946 3.4.24.35 gelatinase B central nervous system localized mainly in the cytoplasm of neoplastic astrocytes 734590 3.4.24.56 insulysin central nervous system - 696530 3.4.24.61 nardilysin central nervous system - 710043 3.4.24.7 interstitial collagenase central nervous system - 709370 3.4.24.B11 ADAMTS1 endopeptidase central nervous system - 668117 3.4.24.B14 neprilysin-2 central nervous system - 754689 3.5.1.15 aspartoacylase central nervous system immunohistochemical localization analysis, high enzyme content in oligodendrocytes along with CC1, and in white matter, including the corpus callosum and the cerebellar white matter, less abundant enzyme content in grey matter, including cerebral cortex, descending neuronal fibers, and microglial cells, no enzyme in astroyctes and forebrain, overview 669635 3.5.1.2 glutaminase central nervous system GLS1 669950 3.6.4.13 RNA helicase central nervous system - 712098 3.6.4.6 vesicle-fusing ATPase central nervous system - 686724 3.6.4.6 vesicle-fusing ATPase central nervous system mRNA for Hez-NSF is present throughout the embryonic, larval and pupal development 667820 3.6.5.2 small monomeric GTPase central nervous system - 734348 4.1.1.19 arginine decarboxylase central nervous system - 747422 4.1.1.29 sulfinoalanine decarboxylase central nervous system - 746938 4.1.2.27 sphinganine-1-phosphate aldolase central nervous system high expression rate 728089 4.2.1.1 carbonic anhydrase central nervous system - 666735, 748270 4.2.1.22 cystathionine beta-synthase central nervous system cystathionine beta-synthase is associated with the generation and/or differentiation of the radial glia/astrocyte lineage cells in the developing central nervous system 664879 4.2.99.18 DNA-(apurinic or apyrimidinic site) lyase central nervous system APE1 is highly expressed in selected regions of the central nervous system 690474 4.3.2.5 peptidylamidoglycolate lyase central nervous system - 666112 4.6.1.2 guanylate cyclase central nervous system atypical sGC primarily expressed 681233 5.1.1.10 amino-acid racemase central nervous system DAR1 is localized to the medial region of the cerebral ganglion where the F- and C-clusters are situated 715591 5.1.1.18 serine racemase central nervous system - -, 727245, 728085 5.3.99.2 Prostaglandin-D synthase central nervous system - 3109, 705932 5.6.2.1 DNA topoisomerase central nervous system level of topo I increases from birth to maturity and decreases, more significantly in males, with senescence 662523 5.6.2.2 DNA topoisomerase (ATP-hydrolysing) central nervous system - -, 714804 6.3.1.17 beta-citrylglutamate synthase central nervous system - 725404 6.3.2.41 N-acetylaspartylglutamate synthase central nervous system - 725404 6.3.2.42 N-acetylaspartylglutamylglutamate synthase central nervous system highest expression levels in the brain stem and spinal cord, almost undetectable in the neocortex 725423 6.3.2.B11 beta-citrylglutamate synthase central nervous system - 725404 6.4.1.3 propionyl-CoA carboxylase central nervous system adult, PCC together with methylmalonyl-CoA mutase and in whole rat embryonic central nervous system, both at E15.5 and E18.5 705936 6.4.1.3 propionyl-CoA carboxylase central nervous system PCCalpha is present in all regions of the central nervous system. PCCalpha is present in the whole embryonic central nervous system, both at E15.5 and E18.5, predominantely in the periventricular zones of telencephalon, midbrain and rhombencephalon 705936 7.2.2.13 Na+/K+-exchanging ATPase central nervous system - 246966, 734529 7.2.2.8 P-type Cu+ transporter central nervous system - 734662