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Literature summary for 6.3.1.2 extracted from
- Inhibitors of glutamine synthetase and their potential application in medicine (2008), Mini Rev. Med. Chem., 8, 869-878.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| (1,4-diamino-4-oxobutyl)phosphonic acid | - |
Rattus norvegicus |  |
| (1-amino-4-methoxy-4-oxobutyl)phosphonic acid | - |
Rattus norvegicus | |
| (1R,3R)-1-amino-3-(hydroxy(methyl)phosphoryl)cyclohexanecarboxylic acid | - |
Escherichia coli | |
| (1R,3R)-1-amino-3-(hydroxy(methyl)phosphoryl)cyclohexanecarboxylic acid | - |
Ovis aries | |
| (1R,3R)-1-amino-3-(hydroxy(methyl)phosphoryl)cyclohexanecarboxylic acid | - |
Sorghum sp. | |
| (1R,3R)-1-amino-3-(hydroxy(methyl)phosphoryl)cyclohexanecarboxylic acid | - |
Spinacia oleracea | |
| (1R,3R)-1-amino-3-(hydroxy(methyl)phosphoryl)cyclohexanecarboxylic acid | - |
Vigna radiata | |
| (1R,3R)-1-amino-3-(hydroxy(methyl)phosphoryl)cyclopentanecarboxylic acid | racemic mixture | Vigna radiata | |
| (2R,3S)-3-aminooxetane-2-carboxylic acid | - |
Bacillus subtilis | |
| (2R,3S)-3-aminooxetane-2-carboxylic acid | - |
Spinacia oleracea | |
| (2S)-2-amino-4-(hydroxyamino)butanoic acid | - |
Bradyrhizobium japonicum | |
| (2S)-2-amino-4-(hydroxyamino)butanoic acid | - |
Ovis aries | |
| (2S)-2-amino-4-[(1-aminoethyl)(hydroxy)phosphoryl]butanoic acid | - |
Escherichia coli | |
| (2S)-2-amino-4-[(1-aminoethyl)(hydroxy)phosphoryl]butanoic acid | - |
Spinacia oleracea | |
| (2S)-2-amino-4-[(2-aminoethyl)(hydroxy)phosphoryl]butanoic acid | - |
Spinacia oleracea | |
| (2S)-2-amino-4-[(3S)-3-hydroxy-2-oxoazetidin-3-yl]butanoic acid | irrversible | Pisum sativum | |
| (2S)-2-amino-4-[(aminomethyl)(hydroxy)phosphoryl]butanoic acid | - |
Escherichia coli | |
| (2S)-2-amino-4-[(aminomethyl)(hydroxy)phosphoryl]butanoic acid | - |
Spinacia oleracea | |
| (2S)-2-amino-4-[hydroxy(hydroxymethyl)phosphoryl]butanoic acid | - |
Escherichia coli | |
| (2S)-2-amino-4-[hydroxy(hydroxymethyl)phosphoryl]butanoic acid | - |
Spinacia oleracea | |
| (2S)-2-amino-4-[hydroxy(nitroso)amino]butanoic acid | - |
Mus musculus | |
| (3,4-diamino-4-oxobutyl)methylphosphinic acid | - |
Rattus norvegicus | |
| (3-amino-4-methoxy-4-oxobutyl)methylphosphinic acid | - |
Rattus norvegicus | |
| (R)-methionine sulfoximine phosphate | weak inhibition compared to the S-enantiomer | Escherichia coli | |
| (R)-methionine sulfoximine phosphate | weak inhibition compared to the S-enantiomer | Mycobacterium tuberculosis | |
| (R)-methionine sulfoximine phosphate | weak inhibition compared to the S-enantiomer | Ovis aries | |
| (R)-methionine sulfoximine phosphate | weak inhibition compared to the S-enantiomer | Pisum sativum | |
| (R)-methionine sulfoximine phosphate | weak inhibition compared to the S-enantiomer | Spinacia oleracea | |
| (S)-methionine sulfoximine phosphate | irreversible, reaction mechanism with required phosphorylation of the inhibitor molecule in the same way as substrate L-glutamate is phosphorylated | Escherichia coli | |
| (S)-methionine sulfoximine phosphate | irreversible, reaction mechanism with required phosphorylation of the inhibitor molecule in the same way as substrate L-glutamate is phosphorylated | Mycobacterium tuberculosis | |
| (S)-methionine sulfoximine phosphate | irreversible, reaction mechanism with required phosphorylation of the inhibitor molecule in the same way as substrate L-glutamate is phosphorylated | Ovis aries | |
| (S)-methionine sulfoximine phosphate | irreversible, reaction mechanism with required phosphorylation of the inhibitor molecule in the same way as substrate L-glutamate is phosphorylated | Pisum sativum | |
| (S)-methionine sulfoximine phosphate | irreversible, reaction mechanism with required phosphorylation of the inhibitor molecule in the same way as substrate L-glutamate is phosphorylated | Spinacia oleracea | |
| ([[2-(4-hydroxyphenyl)ethyl]amino]methanediyl)bis(phosphonic acid) | - |
Oryza sativa | |
| 2-amino-2-ethyl-4-(S-methylsulfonimidoyl)butanoic acid | 41% inhibition at 0.4 mM | Escherichia coli | |
| 2-amino-2-ethyl-4-[hydroxy(methyl)phosphoryl]butanoic acid | - |
Ovis aries | |
| 2-amino-2-ethyl-4-[hydroxy(methyl)phosphoryl]butanoic acid | - |
Sorghum sp. | |
| 2-amino-2-ethyl-4-[hydroxy(methyl)phosphoryl]butanoic acid | - |
Spinacia oleracea | |
| 2-amino-4-(S-ethylsulfonimidoyl)butanoic acid | 76.4% inhibition at 10 mM | Escherichia coli | |
| 2-amino-4-(S-propylsulfonimidoyl)butanoic acid | 35.8% inhibition at 20 mM | Escherichia coli | |
| 2-amino-4-hydroxyglutaric acid | - |
Chlorella sp. | |
| 2-amino-4-[(3,4-dichlorobenzyl)(hydroxy)phosphoryl]butanoic acid | 20% inhibition at 12.5 mM | Pisum sativum | |
| 2-amino-4-[(3,5-dimethylbenzyl)(hydroxy)phosphoryl]butanoic acid | 20% inhibition at 12.5 mM | Pisum sativum | |
| 2-amino-4-[(4-bromobenzyl)(hydroxy)phosphoryl]butanoic acid | 20% inhibition at 12.5 mM | Pisum sativum | |
| 2-amino-4-[(carboxymethyl)(hydroxy)phosphoryl]butanoic acid | 20% inhibition at 12.5 mM | Pisum sativum | |
| 2-amino-4-[(phosphonomethyl)sulfonyl]butanoic acid | - |
Ovis aries | |
| 2-amino-4-[(phosphonomethyl)sulfonyl]butanoic acid | 51% inhibition at 0.5 mM | Spinacia oleracea | |
| 2-amino-4-[benzyl(hydroxy)phosphoryl]butanoic acid | 30% inhibition at 12.5 mM | Pisum sativum | |
| 2-amino-4-[ethyl(hydroxy)phosphoryl]butanoic acid | - |
Columba sp. | |
| 2-amino-4-[ethyl(hydroxy)phosphoryl]butanoic acid | - |
Pisum sativum | |
| 2-amino-4-[hydroxy(oxido)phosphanyl]butanoic acid | 35% inhibition at 12.5 mM | Pisum sativum | |
| 2-amino-4-[hydroxy(phenyl)phosphoryl]butanoic acid | 30% inhibition at 0.5 mM | Columba sp. | |
| 2-amino-4-[hydroxy(phosphonomethyl)amino]butanoic acid | 50% inhibition at 0.5 mM | Spinacia oleracea | |
| 2-amino-4-[hydroxy(phosphonomethyl)phosphoryl]butanoic acid | - |
Escherichia coli | |
| 2-amino-4-[hydroxy(phosphonomethyl)phosphoryl]butanoic acid | - |
Ovis aries | |
| 2-amino-4-[hydroxy(phosphonomethyl)phosphoryl]butanoic acid | - |
Pisum sativum | |
| 2-amino-4-[methyl(phosphonomethyl)amino]butanoic acid | 29% inhibition at 0.5 mM | Spinacia oleracea | |
| 2-amino-4-[methyl(phosphonomethyl)phosphoryl]butanoic acid | - |
Pisum sativum | |
| 2-[(diphosphonomethyl)amino]pyridine-3-carboxylic acid | - |
Oryza sativa | |
| 3-amino-5-[hydroxy(methyl)phosphoryl]tetrahydrofuran-3-carboxylic acid | - |
Vigna radiata | |
| 3-[(diphosphonomethyl)amino]benzoic acid | - |
Oryza sativa | |
| 3-[(phosphonoacetyl)amino]alanine | - |
Escherichia coli | |
| 3-[(phosphonoacetyl)amino]alanine | - |
Pisum sativum | |
| 4-(S-ethylsulfonimidoyl)isovaline | 25.8% inhibition at 2 mM | Escherichia coli | |
| 4-(S-methylsulfonimidoyl)isovaline | 80% inhibition at 0.1 mM | Escherichia coli | |
| 4-(S-propylsulfonimidoyl)isovaline | 34.6% inhibition at 20 mM | Escherichia coli | |
| 4-amino-4-phosphonobutanoic acid | - |
Rattus norvegicus | |
| 4-amino-4-phosphonopentanoic acid | - |
Rattus norvegicus | |
| 4-amino-4-[hydroxy(methyl)phosphoryl]butanoic acid | - |
Rattus norvegicus | |
| 4-amino-4-[hydroxy(methyl)phosphoryl]pentanoic acid | - |
Rattus norvegicus | |
| 4-fluoroglutamic acid | - |
Chlorella sp. | |
| 4-phosphonohomoserine | - |
Escherichia coli | |
| 4-phosphonohomoserine | - |
Ovis aries | |
| 4-phosphonohomoserine | - |
Sorghum sp. | |
| 4-phosphonohomoserine | - |
Spinacia oleracea | |
| 4-phosphonohomoserine | - |
Vigna radiata | |
| 4-phosphonoisovaline | - |
Rattus norvegicus | |
| 4-phosphononorvaline | - |
Escherichia coli | |
| 4-phosphononorvaline | - |
Ovis aries | |
| 4-phosphononorvaline | - |
Sorghum sp. | |
| 4-phosphononorvaline | - |
Spinacia oleracea | |
| 4-phosphononorvaline | - |
Vigna radiata | |
| 4-[hydroxy(methyl)phosphoryl]isovaline | - |
Escherichia coli | |
| 4-[hydroxy(methyl)phosphoryl]isovaline | - |
Ovis aries | |
| 4-[hydroxy(methyl)phosphoryl]isovaline | - |
Rattus norvegicus | |
| 4-[hydroxy(methyl)phosphoryl]isovaline | - |
Sorghum sp. | |
| 4-[hydroxy(methyl)phosphoryl]isovaline | - |
Spinacia oleracea | |
| 5-oxo-6-phosphononorleucine | - |
Escherichia coli | |
| 5-oxo-6-phosphononorleucine | - |
Ovis aries | |
| 5-oxo-6-phosphononorleucine | - |
Pisum sativum | |
| 5-oxolysine | - |
Salmonella enterica subsp. enterica serovar Typhimurium | |
| 5-oxolysine | isozyme GS1; isozyme GS2 | Zea mays | |
| 5-[(3-amino-3-carboxypropyl)(hydroxy)phosphoryl]norvaline | 20% inhibition at 12.5 mM | Pisum sativum | |
| D,L-phosphinothricin | - |
Oryza sativa | |
| L-glutamyl gamma-phosphinic acid | - |
Columba sp. | |
| L-glutamyl gamma-phosphinic acid | - |
Escherichia coli | |
| methionine sulfone | - |
Escherichia coli | |
| methionine sulfone amine | - |
Escherichia coli | |
| methionine sulfoxide | - |
Escherichia coli | |
| methionine sulfoximine | - |
Ovis aries | |
| methionine sulfoximine | - |
Pisum sativum | |
| methionine sulfoximine | - |
Spinacia oleracea | |
| additional information | structure-activity relationships and inhibitor design, overview | Bacillus subtilis | |
| additional information | structure-activity relationships and inhibitor design, overview | Beta vulgaris | |
| additional information | structure-activity relationships and inhibitor design, overview | Bradyrhizobium japonicum | |
| additional information | structure-activity relationships and inhibitor design, overview | Chlorella sp. | |
| additional information | structure-activity relationships and inhibitor design, overview | Columba sp. | |
| additional information | structure-activity relationships and inhibitor design, overview | Escherichia coli | |
| additional information | structure-activity relationships and inhibitor design, overview | Homo sapiens | |
| additional information | structure-activity relationships and inhibitor design, overview; structure-activity relationships and inhibitor design, overview | Hordeum vulgare | |
| additional information | structure-activity relationships and inhibitor design, overview | Mus musculus | |
| additional information | structure-activity relationships and inhibitor design, overview | Mycobacterium tuberculosis | |
| additional information | structure-activity relationships and inhibitor design, overview | Oryza sativa | |
| additional information | structure-activity relationships and inhibitor design, overview | Ovis aries | |
| additional information | structure-activity relationships and inhibitor design, overview | Pisum sativum | |
| additional information | structure-activity relationships and inhibitor design, overview | Rattus norvegicus | |
| additional information | structure-activity relationships and inhibitor design, overview | Salmonella enterica subsp. enterica serovar Typhimurium | |
| additional information | structure-activity relationships and inhibitor design, overview | Senna obtusifolia | |
| additional information | structure-activity relationships and inhibitor design, overview | Sorghum sp. | |
| additional information | structure-activity relationships and inhibitor design, overview | Spinacia oleracea | |
| additional information | structure-activity relationships and inhibitor design, overview | Synechocystis sp. | |
| additional information | structure-activity relationships and inhibitor design, overview | Triticum aestivum | |
| additional information | structure-activity relationships and inhibitor design, overview | Vigna radiata | |
| additional information | structure-activity relationships and inhibitor design, overview | Zea mays | |
| O-acetyl-4-phosphonohomoserine | - |
Escherichia coli | |
| O-acetyl-4-phosphonohomoserine | - |
Sorghum sp. | |
| P-ethyl gamma-phosphinic L-glutamate | - |
Columba sp. | |
| Phosphinothricin | isolated from Streptomyces viridochromogenes | Beta vulgaris | |
| Phosphinothricin | isolated from Streptomyces viridochromogenes | Bradyrhizobium japonicum | |
| Phosphinothricin | isolated from Streptomyces viridochromogenes | Escherichia coli | |
| Phosphinothricin | isolated from Streptomyces viridochromogenes; isolated from Streptomyces viridochromogenes | Hordeum vulgare | |
| Phosphinothricin | isolated from Streptomyces viridochromogenes | Ovis aries | |
| Phosphinothricin | isolated from Streptomyces viridochromogenes | Pisum sativum | |
| Phosphinothricin | isolated from Streptomyces viridochromogenes | Rattus norvegicus | |
| Phosphinothricin | isolated from Streptomyces viridochromogenes | Senna obtusifolia | |
| Phosphinothricin | isolated from Streptomyces viridochromogenes | Sorghum sp. | |
| Phosphinothricin | isolated from Streptomyces viridochromogenes | Spinacia oleracea | |
| Phosphinothricin | isolated from Streptomyces viridochromogenes | Triticum aestivum | |
| Phosphinothricin | isolated from Streptomyces viridochromogenes | Vigna radiata | |
| Phosphinothricin | isolated from Streptomyces viridochromogenes | Zea mays | |
| [(cyclohexylamino)methanediyl]bis(phosphonic acid) | - |
Oryza sativa | |
| [(pyridin-2-ylamino)methanediyl]bis(phosphonic acid) | - |
Oryza sativa | |
| [1-amino-3-(S-methylsulfonimidoyl)propyl]phosphonic acid | - |
Escherichia coli | |
| [[(3,5-dichlorophenyl)amino]methanediyl]bis(phosphonic acid) | - |
Oryza sativa | |
| [[(3-nitrophenyl)amino]methanediyl]bis(phosphonic acid) | - |
Oryza sativa | |
| [[(4-methylphenyl)amino]methanediyl]bis(phosphonic acid) | - |
Oryza sativa | |
| [[(5-chloropyridin-2-yl)amino]methanediyl]bis(phosphonic acid) | - |
Oryza sativa | |
| [[(pyridin-2-ylmethyl)amino]methanediyl]bis(phosphonic acid) | - |
Oryza sativa | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| chloroplast | - |
Spinacia oleracea | 9507 | - |
| cytosol | - |
Spinacia oleracea | 5829 | - |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mg2+ | - |
Beta vulgaris | |
| Mg2+ | - |
Escherichia coli | |
| Mg2+ | - |
Triticum aestivum | |
| Mg2+ | - |
Ovis aries | |
| Mg2+ | - |
Bradyrhizobium japonicum | |
| Mg2+ | - |
Hordeum vulgare | |
| Mg2+ | - |
Spinacia oleracea | |
| Mg2+ | - |
Pisum sativum | |
| Mg2+ | - |
Zea mays | |
| Mg2+ | - |
Vigna radiata | |
| Mg2+ | - |
Oryza sativa | |
| Mg2+ | - |
Sorghum sp. | |
| Mg2+ | - |
Chlorella sp. | |
| Mg2+ | - |
Columba sp. | |
| Mg2+ | - |
Rattus norvegicus | |
| Mg2+ | - |
Senna obtusifolia | |
| Mg2+ | - |
Salmonella enterica subsp. enterica serovar Typhimurium | |
| Mg2+ | - |
Synechocystis sp. | |
| Mg2+ | - |
Homo sapiens | |
| Mg2+ | - |
Mus musculus | |
| Mg2+ | - |
Bacillus subtilis | |
| Mg2+ | - |
Mycobacterium tuberculosis | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + L-glutamate + NH3 | Beta vulgaris | - |
ADP + phosphate + L-glutamine | - |
? | |
| ATP + L-glutamate + NH3 | Escherichia coli | - |
ADP + phosphate + L-glutamine | - |
? | |
| ATP + L-glutamate + NH3 | Triticum aestivum | - |
ADP + phosphate + L-glutamine | - |
? | |
| ATP + L-glutamate + NH3 | Ovis aries | - |
ADP + phosphate + L-glutamine | - |
? | |
| ATP + L-glutamate + NH3 | Bradyrhizobium japonicum | - |
ADP + phosphate + L-glutamine | - |
? | |
| ATP + L-glutamate + NH3 | Hordeum vulgare | - |
ADP + phosphate + L-glutamine | - |
? | |
| ATP + L-glutamate + NH3 | Spinacia oleracea | - |
ADP + phosphate + L-glutamine | - |
? | |
| ATP + L-glutamate + NH3 | Pisum sativum | - |
ADP + phosphate + L-glutamine | - |
? | |
| ATP + L-glutamate + NH3 | Zea mays | - |
ADP + phosphate + L-glutamine | - |
? | |
| ATP + L-glutamate + NH3 | Vigna radiata | - |
ADP + phosphate + L-glutamine | - |
? | |
| ATP + L-glutamate + NH3 | Oryza sativa | - |
ADP + phosphate + L-glutamine | - |
? | |
| ATP + L-glutamate + NH3 | Sorghum sp. | - |
ADP + phosphate + L-glutamine | - |
? | |
| ATP + L-glutamate + NH3 | Chlorella sp. | - |
ADP + phosphate + L-glutamine | - |
? | |
| ATP + L-glutamate + NH3 | Columba sp. | - |
ADP + phosphate + L-glutamine | - |
? | |
| ATP + L-glutamate + NH3 | Rattus norvegicus | - |
ADP + phosphate + L-glutamine | - |
? | |
| ATP + L-glutamate + NH3 | Senna obtusifolia | - |
ADP + phosphate + L-glutamine | - |
? | |
| ATP + L-glutamate + NH3 | Salmonella enterica subsp. enterica serovar Typhimurium | - |
ADP + phosphate + L-glutamine | - |
? | |
| ATP + L-glutamate + NH3 | Synechocystis sp. | - |
ADP + phosphate + L-glutamine | - |
? | |
| ATP + L-glutamate + NH3 | Homo sapiens | - |
ADP + phosphate + L-glutamine | - |
? | |
| ATP + L-glutamate + NH3 | Mus musculus | - |
ADP + phosphate + L-glutamine | - |
? | |
| ATP + L-glutamate + NH3 | Bacillus subtilis | - |
ADP + phosphate + L-glutamine | - |
? | |
| ATP + L-glutamate + NH3 | Mycobacterium tuberculosis | - |
ADP + phosphate + L-glutamine | - |
? | |
| ATP + L-glutamate + NH3 | Mycobacterium tuberculosis H37Rv | - |
ADP + phosphate + L-glutamine | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bacillus subtilis | P12425 | - |
- |
| Beta vulgaris | - |
isozyme GS2 | - |
| Bradyrhizobium japonicum | - |
isozyme GS2 | - |
| Chlorella sp. | - |
- |
- |
| Columba sp. | - |
- |
- |
| Escherichia coli | - |
- |
- |
| Homo sapiens | P15104 | - |
- |
| Hordeum vulgare | - |
isozyme GS1 | - |
| Hordeum vulgare | P13564 | isozyme GS2 | - |
| Mus musculus | P15105 | - |
- |
| Mycobacterium tuberculosis | P9WN39 | - |
- |
| Mycobacterium tuberculosis H37Rv | P9WN39 | - |
- |
| Oryza sativa | - |
- |
- |
| Ovis aries | - |
- |
- |
| Pisum sativum | - |
- |
- |
| Rattus norvegicus | P09606 | - |
- |
| Salmonella enterica subsp. enterica serovar Typhimurium | P0A1P6 | - |
- |
| Senna obtusifolia | - |
isozyme GS2 | - |
| Sorghum sp. | - |
- |
- |
| Spinacia oleracea | - |
- |
- |
| Synechocystis sp. | P77961 | - |
- |
| Triticum aestivum | - |
isozyme GS2 | - |
| Vigna radiata | - |
- |
- |
| Zea mays | - |
isozyme GS1 | - |
| Zea mays | - |
isozyme GS2 | - |
Reaction
| Reaction | Comment | Organism | Reaction ID |
|---|---|---|---|
| ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine | reaction mechanism | Beta vulgaris | |
| ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine | reaction mechanism | Triticum aestivum | |
| ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine | reaction mechanism | Ovis aries | |
| ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine | reaction mechanism | Bradyrhizobium japonicum | |
| ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine | reaction mechanism | Hordeum vulgare | |
| ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine | reaction mechanism | Spinacia oleracea | |
| ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine | reaction mechanism | Pisum sativum | |
| ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine | reaction mechanism | Zea mays | |
| ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine | reaction mechanism | Vigna radiata | |
| ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine | reaction mechanism | Oryza sativa | |
| ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine | reaction mechanism | Sorghum sp. | |
| ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine | reaction mechanism | Chlorella sp. | |
| ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine | reaction mechanism | Columba sp. | |
| ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine | reaction mechanism | Rattus norvegicus | |
| ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine | reaction mechanism | Senna obtusifolia | |
| ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine | reaction mechanism | Salmonella enterica subsp. enterica serovar Typhimurium | |
| ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine | reaction mechanism | Synechocystis sp. | |
| ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine | reaction mechanism | Homo sapiens | |
| ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine | reaction mechanism | Mus musculus | |
| ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine | reaction mechanism | Bacillus subtilis | |
| ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine | reaction mechanism | Mycobacterium tuberculosis | |
| ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine | reaction mechanism and transition state analogue, overview | Escherichia coli |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brain | - |
Ovis aries | - |
| leaf | - |
Spinacia oleracea | - |
| leaf | - |
Pisum sativum | - |
| liver | - |
Columba sp. | - |
| liver | - |
Rattus norvegicus | - |
| seed | - |
Sorghum sp. | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + L-glutamate + NH3 | - |
Beta vulgaris | ADP + phosphate + L-glutamine | - |
? | |
| ATP + L-glutamate + NH3 | - |
Escherichia coli | ADP + phosphate + L-glutamine | - |
? | |
| ATP + L-glutamate + NH3 | - |
Triticum aestivum | ADP + phosphate + L-glutamine | - |
? | |
| ATP + L-glutamate + NH3 | - |
Ovis aries | ADP + phosphate + L-glutamine | - |
? | |
| ATP + L-glutamate + NH3 | - |
Bradyrhizobium japonicum | ADP + phosphate + L-glutamine | - |
? | |
| ATP + L-glutamate + NH3 | - |
Hordeum vulgare | ADP + phosphate + L-glutamine | - |
? | |
| ATP + L-glutamate + NH3 | - |
Spinacia oleracea | ADP + phosphate + L-glutamine | - |
? | |
| ATP + L-glutamate + NH3 | - |
Pisum sativum | ADP + phosphate + L-glutamine | - |
? | |
| ATP + L-glutamate + NH3 | - |
Zea mays | ADP + phosphate + L-glutamine | - |
? | |
| ATP + L-glutamate + NH3 | - |
Vigna radiata | ADP + phosphate + L-glutamine | - |
? | |
| ATP + L-glutamate + NH3 | - |
Oryza sativa | ADP + phosphate + L-glutamine | - |
? | |
| ATP + L-glutamate + NH3 | - |
Sorghum sp. | ADP + phosphate + L-glutamine | - |
? | |
| ATP + L-glutamate + NH3 | - |
Chlorella sp. | ADP + phosphate + L-glutamine | - |
? | |
| ATP + L-glutamate + NH3 | - |
Columba sp. | ADP + phosphate + L-glutamine | - |
? | |
| ATP + L-glutamate + NH3 | - |
Rattus norvegicus | ADP + phosphate + L-glutamine | - |
? | |
| ATP + L-glutamate + NH3 | - |
Senna obtusifolia | ADP + phosphate + L-glutamine | - |
? | |
| ATP + L-glutamate + NH3 | - |
Salmonella enterica subsp. enterica serovar Typhimurium | ADP + phosphate + L-glutamine | - |
? | |
| ATP + L-glutamate + NH3 | - |
Synechocystis sp. | ADP + phosphate + L-glutamine | - |
? | |
| ATP + L-glutamate + NH3 | - |
Homo sapiens | ADP + phosphate + L-glutamine | - |
? | |
| ATP + L-glutamate + NH3 | - |
Mus musculus | ADP + phosphate + L-glutamine | - |
? | |
| ATP + L-glutamate + NH3 | - |
Bacillus subtilis | ADP + phosphate + L-glutamine | - |
? | |
| ATP + L-glutamate + NH3 | - |
Mycobacterium tuberculosis | ADP + phosphate + L-glutamine | - |
? | |
| ATP + L-glutamate + NH3 | a two-step reaction with phosphorylation of L-glutamate by ATP to give gamma-glutamyl phosphate followed by addition of ammonia and release of phosphate resulting in L-glutamine, phopshate and ADP | Hordeum vulgare | ADP + phosphate + L-glutamine | - |
? | |
| ATP + L-glutamate + NH3 | a two-step reaction with phosphorylation of L-glutamate by ATP to give gamma-glutamyl phosphate followed by addition of ammonia and release of phosphate resulting in L-glutamine, phopshate and ADP | Spinacia oleracea | ADP + phosphate + L-glutamine | - |
? | |
| ATP + L-glutamate + NH3 | a two-step reaction with phosphorylation of L-glutamate by ATP to give gamma-glutamyl phosphate followed by addition of ammonia and release of phosphate resulting in L-glutamine, phopshate and ADP | Pisum sativum | ADP + phosphate + L-glutamine | - |
? | |
| ATP + L-glutamate + NH3 | a two-step reaction with phosphorylation of L-glutamate by ATP to give gamma-glutamyl phosphate followed by addition of ammonia and release of phosphate resulting in L-glutamine, phopshate and ADP | Rattus norvegicus | ADP + phosphate + L-glutamine | - |
? | |
| ATP + L-glutamate + NH3 | a two-step reaction with phosphorylation of L-glutamate by ATP to give gamma-glutamyl phosphate followed by addition of ammonia and release of phosphate resulting in L-glutamine, phopshate and ADP | Mycobacterium tuberculosis | ADP + phosphate + L-glutamine | - |
? | |
| ATP + L-glutamate + NH3 | a two-step reaction with phosphorylation of L-glutamate by ATP to give gamma-glutamyl phosphate followed by addition of ammonia and release of phosphate resulting in L-glutamine, phosphate and ADP | Beta vulgaris | ADP + phosphate + L-glutamine | - |
? | |
| ATP + L-glutamate + NH3 | a two-step reaction with phosphorylation of L-glutamate by ATP to give gamma-glutamyl phosphate followed by addition of ammonia and release of phosphate resulting in L-glutamine, phosphate and ADP | Escherichia coli | ADP + phosphate + L-glutamine | - |
? | |
| ATP + L-glutamate + NH3 | a two-step reaction with phosphorylation of L-glutamate by ATP to give gamma-glutamyl phosphate followed by addition of ammonia and release of phosphate resulting in L-glutamine, phosphate and ADP | Triticum aestivum | ADP + phosphate + L-glutamine | - |
? | |
| ATP + L-glutamate + NH3 | a two-step reaction with phosphorylation of L-glutamate by ATP to give gamma-glutamyl phosphate followed by addition of ammonia and release of phosphate resulting in L-glutamine, phosphate and ADP | Ovis aries | ADP + phosphate + L-glutamine | - |
? | |
| ATP + L-glutamate + NH3 | a two-step reaction with phosphorylation of L-glutamate by ATP to give gamma-glutamyl phosphate followed by addition of ammonia and release of phosphate resulting in L-glutamine, phosphate and ADP | Bradyrhizobium japonicum | ADP + phosphate + L-glutamine | - |
? | |
| ATP + L-glutamate + NH3 | a two-step reaction with phosphorylation of L-glutamate by ATP to give gamma-glutamyl phosphate followed by addition of ammonia and release of phosphate resulting in L-glutamine, phosphate and ADP | Zea mays | ADP + phosphate + L-glutamine | - |
? | |
| ATP + L-glutamate + NH3 | a two-step reaction with phosphorylation of L-glutamate by ATP to give gamma-glutamyl phosphate followed by addition of ammonia and release of phosphate resulting in L-glutamine, phosphate and ADP | Vigna radiata | ADP + phosphate + L-glutamine | - |
? | |
| ATP + L-glutamate + NH3 | a two-step reaction with phosphorylation of L-glutamate by ATP to give gamma-glutamyl phosphate followed by addition of ammonia and release of phosphate resulting in L-glutamine, phosphate and ADP | Oryza sativa | ADP + phosphate + L-glutamine | - |
? | |
| ATP + L-glutamate + NH3 | a two-step reaction with phosphorylation of L-glutamate by ATP to give gamma-glutamyl phosphate followed by addition of ammonia and release of phosphate resulting in L-glutamine, phosphate and ADP | Sorghum sp. | ADP + phosphate + L-glutamine | - |
? | |
| ATP + L-glutamate + NH3 | a two-step reaction with phosphorylation of L-glutamate by ATP to give gamma-glutamyl phosphate followed by addition of ammonia and release of phosphate resulting in L-glutamine, phosphate and ADP | Chlorella sp. | ADP + phosphate + L-glutamine | - |
? | |
| ATP + L-glutamate + NH3 | a two-step reaction with phosphorylation of L-glutamate by ATP to give gamma-glutamyl phosphate followed by addition of ammonia and release of phosphate resulting in L-glutamine, phosphate and ADP | Columba sp. | ADP + phosphate + L-glutamine | - |
? | |
| ATP + L-glutamate + NH3 | a two-step reaction with phosphorylation of L-glutamate by ATP to give gamma-glutamyl phosphate followed by addition of ammonia and release of phosphate resulting in L-glutamine, phosphate and ADP | Senna obtusifolia | ADP + phosphate + L-glutamine | - |
? | |
| ATP + L-glutamate + NH3 | a two-step reaction with phosphorylation of L-glutamate by ATP to give gamma-glutamyl phosphate followed by addition of ammonia and release of phosphate resulting in L-glutamine, phosphate and ADP | Salmonella enterica subsp. enterica serovar Typhimurium | ADP + phosphate + L-glutamine | - |
? | |
| ATP + L-glutamate + NH3 | a two-step reaction with phosphorylation of L-glutamate by ATP to give gamma-glutamyl phosphate followed by addition of ammonia and release of phosphate resulting in L-glutamine, phosphate and ADP | Synechocystis sp. | ADP + phosphate + L-glutamine | - |
? | |
| ATP + L-glutamate + NH3 | a two-step reaction with phosphorylation of L-glutamate by ATP to give gamma-glutamyl phosphate followed by addition of ammonia and release of phosphate resulting in L-glutamine, phosphate and ADP | Homo sapiens | ADP + phosphate + L-glutamine | - |
? | |
| ATP + L-glutamate + NH3 | a two-step reaction with phosphorylation of L-glutamate by ATP to give gamma-glutamyl phosphate followed by addition of ammonia and release of phosphate resulting in L-glutamine, phosphate and ADP | Mus musculus | ADP + phosphate + L-glutamine | - |
? | |
| ATP + L-glutamate + NH3 | a two-step reaction with phosphorylation of L-glutamate by ATP to give gamma-glutamyl phosphate followed by addition of ammonia and release of phosphate resulting in L-glutamine, phosphate and ADP | Bacillus subtilis | ADP + phosphate + L-glutamine | - |
? | |
| ATP + L-glutamate + NH3 | - |
Mycobacterium tuberculosis H37Rv | ADP + phosphate + L-glutamine | - |
? | |
| ATP + L-glutamate + NH3 | a two-step reaction with phosphorylation of L-glutamate by ATP to give gamma-glutamyl phosphate followed by addition of ammonia and release of phosphate resulting in L-glutamine, phopshate and ADP | Mycobacterium tuberculosis H37Rv | ADP + phosphate + L-glutamine | - |
? | |
| additional information | structure-activity relationship, overview | Beta vulgaris | ? | - |
? | |
| additional information | structure-activity relationship, overview | Escherichia coli | ? | - |
? | |
| additional information | structure-activity relationship, overview | Triticum aestivum | ? | - |
? | |
| additional information | structure-activity relationship, overview | Ovis aries | ? | - |
? | |
| additional information | structure-activity relationship, overview | Bradyrhizobium japonicum | ? | - |
? | |
| additional information | structure-activity relationship, overview | Hordeum vulgare | ? | - |
? | |
| additional information | structure-activity relationship, overview | Spinacia oleracea | ? | - |
? | |
| additional information | structure-activity relationship, overview | Pisum sativum | ? | - |
? | |
| additional information | structure-activity relationship, overview | Zea mays | ? | - |
? | |
| additional information | structure-activity relationship, overview | Vigna radiata | ? | - |
? | |
| additional information | structure-activity relationship, overview | Oryza sativa | ? | - |
? | |
| additional information | structure-activity relationship, overview | Sorghum sp. | ? | - |
? | |
| additional information | structure-activity relationship, overview | Chlorella sp. | ? | - |
? | |
| additional information | structure-activity relationship, overview | Columba sp. | ? | - |
? | |
| additional information | structure-activity relationship, overview | Rattus norvegicus | ? | - |
? | |
| additional information | structure-activity relationship, overview | Senna obtusifolia | ? | - |
? | |
| additional information | structure-activity relationship, overview | Salmonella enterica subsp. enterica serovar Typhimurium | ? | - |
? | |
| additional information | structure-activity relationship, overview | Synechocystis sp. | ? | - |
? | |
| additional information | structure-activity relationship, overview | Homo sapiens | ? | - |
? | |
| additional information | structure-activity relationship, overview | Mus musculus | ? | - |
? | |
| additional information | structure-activity relationship, overview | Bacillus subtilis | ? | - |
? | |
| additional information | structure-activity relationship, overview | Mycobacterium tuberculosis | ? | - |
? | |
| additional information | structure-activity relationship, overview | Mycobacterium tuberculosis H37Rv | ? | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| decamer | - |
Beta vulgaris |
| decamer | - |
Triticum aestivum |
| decamer | - |
Ovis aries |
| decamer | - |
Bradyrhizobium japonicum |
| decamer | - |
Hordeum vulgare |
| decamer | - |
Spinacia oleracea |
| decamer | - |
Pisum sativum |
| decamer | - |
Zea mays |
| decamer | - |
Vigna radiata |
| decamer | - |
Sorghum sp. |
| decamer | - |
Chlorella sp. |
| decamer | - |
Columba sp. |
| decamer | - |
Rattus norvegicus |
| decamer | - |
Senna obtusifolia |
| decamer | - |
Homo sapiens |
| decamer | - |
Mus musculus |
| dodecamer | - |
Escherichia coli |
| dodecamer | - |
Oryza sativa |
| dodecamer | - |
Salmonella enterica subsp. enterica serovar Typhimurium |
| dodecamer | - |
Synechocystis sp. |
| dodecamer | - |
Bacillus subtilis |
| dodecamer | - |
Mycobacterium tuberculosis |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Glutamine synthetase | - |
Beta vulgaris |
| Glutamine synthetase | - |
Escherichia coli |
| Glutamine synthetase | - |
Triticum aestivum |
| Glutamine synthetase | - |
Ovis aries |
| Glutamine synthetase | - |
Bradyrhizobium japonicum |
| Glutamine synthetase | - |
Hordeum vulgare |
| Glutamine synthetase | - |
Spinacia oleracea |
| Glutamine synthetase | - |
Pisum sativum |
| Glutamine synthetase | - |
Zea mays |
| Glutamine synthetase | - |
Vigna radiata |
| Glutamine synthetase | - |
Oryza sativa |
| Glutamine synthetase | - |
Sorghum sp. |
| Glutamine synthetase | - |
Chlorella sp. |
| Glutamine synthetase | - |
Columba sp. |
| Glutamine synthetase | - |
Rattus norvegicus |
| Glutamine synthetase | - |
Senna obtusifolia |
| Glutamine synthetase | - |
Salmonella enterica subsp. enterica serovar Typhimurium |
| Glutamine synthetase | - |
Synechocystis sp. |
| Glutamine synthetase | - |
Homo sapiens |
| Glutamine synthetase | - |
Mus musculus |
| Glutamine synthetase | - |
Bacillus subtilis |
| Glutamine synthetase | - |
Mycobacterium tuberculosis |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| ATP | - |
Beta vulgaris | |
| ATP | - |
Escherichia coli | |
| ATP | - |
Triticum aestivum | |
| ATP | - |
Ovis aries | |
| ATP | - |
Bradyrhizobium japonicum | |
| ATP | - |
Hordeum vulgare | |
| ATP | - |
Spinacia oleracea | |
| ATP | - |
Pisum sativum | |
| ATP | - |
Zea mays | |
| ATP | - |
Vigna radiata | |
| ATP | - |
Oryza sativa | |
| ATP | - |
Sorghum sp. | |
| ATP | - |
Chlorella sp. | |
| ATP | - |
Columba sp. | |
| ATP | - |
Rattus norvegicus | |
| ATP | - |
Senna obtusifolia | |
| ATP | - |
Salmonella enterica subsp. enterica serovar Typhimurium | |
| ATP | - |
Synechocystis sp. | |
| ATP | - |
Homo sapiens | |
| ATP | - |
Mus musculus | |
| ATP | - |
Bacillus subtilis | |
| ATP | - |
Mycobacterium tuberculosis | |
Ki Value [mM]
| Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.00000047 | - |
(1R,3R)-1-amino-3-(hydroxy(methyl)phosphoryl)cyclopentanecarboxylic acid | - |
Vigna radiata | |
| 0.0000008 | - |
4-phosphonohomoserine | - |
Vigna radiata | |
| 0.000005 | - |
3-amino-5-[hydroxy(methyl)phosphoryl]tetrahydrofuran-3-carboxylic acid | - |
Vigna radiata | |
| 0.00031 | - |
(1R,3R)-1-amino-3-(hydroxy(methyl)phosphoryl)cyclohexanecarboxylic acid | - |
Vigna radiata | |
| 0.00059 | - |
(2S)-2-amino-4-[(aminomethyl)(hydroxy)phosphoryl]butanoic acid | - |
Escherichia coli | |
| 0.0011 | - |
Phosphinothricin | - |
Escherichia coli | |
| 0.0016 | - |
4-phosphonohomoserine | - |
Escherichia coli | |
| 0.0018 | - |
(2S)-2-amino-4-[(aminomethyl)(hydroxy)phosphoryl]butanoic acid | - |
Spinacia oleracea | |
| 0.002 | - |
methionine sulfoximine | - |
Escherichia coli | |
| 0.002 | - |
Phosphinothricin | isozyme GS1 | Zea mays | |
| 0.0021 | - |
(2S)-2-amino-4-[hydroxy(hydroxymethyl)phosphoryl]butanoic acid | - |
Escherichia coli | |
| 0.003 | - |
Phosphinothricin | - |
Spinacia oleracea | |
| 0.0035 | - |
Phosphinothricin | isozyme GS1 | Hordeum vulgare | |
| 0.0037 | - |
(2S)-2-amino-4-[(1-aminoethyl)(hydroxy)phosphoryl]butanoic acid | - |
Escherichia coli | |
| 0.004 | - |
Phosphinothricin | isozyme GS1 | Zea mays | |
| 0.0057 | - |
4-[hydroxy(methyl)phosphoryl]isovaline | - |
Escherichia coli | |
| 0.006 | - |
Phosphinothricin | isozyme GS2 | Hordeum vulgare | |
| 0.0065 | - |
Phosphinothricin | isozyme GS2 | Beta vulgaris | |
| 0.007 | - |
(2S)-2-amino-4-(hydroxyamino)butanoic acid | - |
Ovis aries | |
| 0.0079 | - |
(2S)-2-amino-4-[(aminomethyl)(hydroxy)phosphoryl]butanoic acid | - |
Spinacia oleracea | |
| 0.008 | - |
Phosphinothricin | - |
Sorghum sp. | |
| 0.008 | - |
Phosphinothricin | isozyme GS2 | Bradyrhizobium japonicum | |
| 0.0085 | - |
(2S)-2-amino-4-[hydroxy(hydroxymethyl)phosphoryl]butanoic acid | - |
Spinacia oleracea | |
| 0.0085 | - |
Phosphinothricin | isozyme GS2 | Senna obtusifolia | |
| 0.009 | - |
Phosphinothricin | isozyme GS2 | Triticum aestivum | |
| 0.012 | - |
4-phosphonohomoserine | - |
Spinacia oleracea | |
| 0.014 | - |
4-phosphonohomoserine | - |
Sorghum sp. | |
| 0.016 | - |
4-[hydroxy(methyl)phosphoryl]isovaline | - |
Spinacia oleracea | |
| 0.0176 | - |
(2S)-2-amino-4-[(1-aminoethyl)(hydroxy)phosphoryl]butanoic acid | - |
Spinacia oleracea | |
| 0.02 | - |
(1R,3R)-1-amino-3-(hydroxy(methyl)phosphoryl)cyclohexanecarboxylic acid | - |
Sorghum sp. | |
| 0.021 | - |
(2S)-2-amino-4-(hydroxyamino)butanoic acid | - |
Bradyrhizobium japonicum | |
| 0.0216 | - |
(2S)-2-amino-4-[(1-aminoethyl)(hydroxy)phosphoryl]butanoic acid | - |
Spinacia oleracea | |
| 0.022 | - |
2-amino-2-ethyl-4-[hydroxy(methyl)phosphoryl]butanoic acid | - |
Sorghum sp. | |
| 0.024 | - |
(1R,3R)-1-amino-3-(hydroxy(methyl)phosphoryl)cyclohexanecarboxylic acid | - |
Escherichia coli | |
| 0.024 | - |
4-[hydroxy(methyl)phosphoryl]isovaline | - |
Sorghum sp. | |
| 0.025 | - |
4-phosphononorvaline | - |
Escherichia coli | |
| 0.0252 | - |
Phosphinothricin | - |
Ovis aries | |
| 0.032 | - |
2-amino-2-ethyl-4-[hydroxy(methyl)phosphoryl]butanoic acid | - |
Spinacia oleracea | |
| 0.033 | - |
[[(3,5-dichlorophenyl)amino]methanediyl]bis(phosphonic acid) | - |
Oryza sativa | |
| 0.033 | - |
O-acetyl-4-phosphonohomoserine | - |
Escherichia coli | |
| 0.033 | - |
D,L-phosphinothricin | - |
Oryza sativa | |
| 0.04 | - |
5-oxolysine | - |
Salmonella enterica subsp. enterica serovar Typhimurium | |
| 0.0458 | - |
(2S)-2-amino-4-[hydroxy(hydroxymethyl)phosphoryl]butanoic acid | - |
Spinacia oleracea | |
| 0.047 | - |
4-phosphonohomoserine | - |
Ovis aries | |
| 0.05 | - |
2-amino-4-[ethyl(hydroxy)phosphoryl]butanoic acid | - |
Pisum sativum | |
| 0.051 | - |
methionine sulfone amine | - |
Escherichia coli | |
| 0.054 | - |
L-glutamyl gamma-phosphinic acid | - |
Escherichia coli | |
| 0.056 | - |
4-[hydroxy(methyl)phosphoryl]isovaline | - |
Rattus norvegicus | |
| 0.064 | - |
[[(pyridin-2-ylmethyl)amino]methanediyl]bis(phosphonic acid) | - |
Oryza sativa | |
| 0.067 | - |
4-phosphononorvaline | - |
Sorghum sp. | |
| 0.069 | - |
[[(5-chloropyridin-2-yl)amino]methanediyl]bis(phosphonic acid) | - |
Oryza sativa | |
| 0.072 | - |
(1R,3R)-1-amino-3-(hydroxy(methyl)phosphoryl)cyclohexanecarboxylic acid | - |
Spinacia oleracea | |
| 0.073 | - |
Phosphinothricin | - |
Pisum sativum | |
| 0.075 | - |
2-amino-4-[hydroxy(phosphonomethyl)phosphoryl]butanoic acid | - |
Escherichia coli | |
| 0.1 | - |
methionine sulfoximine | - |
Spinacia oleracea | |
| 0.111 | - |
2-amino-2-ethyl-4-[hydroxy(methyl)phosphoryl]butanoic acid | - |
Ovis aries | |
| 0.125 | - |
(1R,3R)-1-amino-3-(hydroxy(methyl)phosphoryl)cyclohexanecarboxylic acid | - |
Ovis aries | |
| 0.125 | - |
4-[hydroxy(methyl)phosphoryl]isovaline | - |
Ovis aries | |
| 0.133 | - |
(2S)-2-amino-4-[(2-aminoethyl)(hydroxy)phosphoryl]butanoic acid | - |
Spinacia oleracea | |
| 0.14 | - |
4-phosphononorvaline | - |
Vigna radiata | |
| 0.161 | - |
methionine sulfoximine | - |
Pisum sativum | |
| 0.17 | - |
[[(4-methylphenyl)amino]methanediyl]bis(phosphonic acid) | - |
Oryza sativa | |
| 0.178 | - |
O-acetyl-4-phosphonohomoserine | - |
Sorghum sp. | |
| 0.21 | - |
methionine sulfoximine | - |
Ovis aries | |
| 0.243 | - |
[(pyridin-2-ylamino)methanediyl]bis(phosphonic acid) | - |
Oryza sativa | |
| 0.25 | - |
2-amino-4-[hydroxy(phosphonomethyl)phosphoryl]butanoic acid | - |
Pisum sativum | |
| 0.31 | - |
3-[(phosphonoacetyl)amino]alanine | - |
Pisum sativum | |
| 0.32 | - |
Phosphinothricin | - |
Rattus norvegicus | |
| 0.32 | - |
(2S)-2-amino-4-[(2-aminoethyl)(hydroxy)phosphoryl]butanoic acid | - |
Spinacia oleracea | |
| 0.334 | - |
2-[(diphosphonomethyl)amino]pyridine-3-carboxylic acid | - |
Oryza sativa | |
| 0.347 | - |
4-phosphononorvaline | - |
Ovis aries | |
| 0.49 | - |
5-oxolysine | - |
Zea mays | |
| 0.492 | - |
4-phosphononorvaline | - |
Spinacia oleracea | |
| 0.59 | - |
5-oxo-6-phosphononorleucine | - |
Pisum sativum | |
| 0.62 | - |
4-fluoroglutamic acid | - |
Chlorella sp. | |
| 0.66 | - |
5-oxo-6-phosphononorleucine | - |
Ovis aries | |
| 0.738 | - |
[[(3-nitrophenyl)amino]methanediyl]bis(phosphonic acid) | - |
Oryza sativa | |
| 0.75 | - |
2-amino-4-[hydroxy(phosphonomethyl)phosphoryl]butanoic acid | - |
Ovis aries | |
| 0.79 | - |
4-amino-4-[hydroxy(methyl)phosphoryl]butanoic acid | - |
Rattus norvegicus | |
| 0.85 | - |
5-oxolysine | - |
Zea mays | |
| 0.91 | - |
3-[(phosphonoacetyl)amino]alanine | - |
Escherichia coli | |
| 1 | - |
(2S)-2-amino-4-[(3S)-3-hydroxy-2-oxoazetidin-3-yl]butanoic acid | - |
Pisum sativum | |
| 1.1 | - |
[(cyclohexylamino)methanediyl]bis(phosphonic acid) | - |
Oryza sativa | |
| 1.2 | - |
(2R,3S)-3-aminooxetane-2-carboxylic acid | - |
Bacillus subtilis | |
| 1.2 | - |
[1-amino-3-(S-methylsulfonimidoyl)propyl]phosphonic acid | - |
Escherichia coli | |
| 1.3 | - |
(2S)-2-amino-4-[hydroxy(nitroso)amino]butanoic acid | - |
Mus musculus | |
| 1.3 | - |
4-amino-4-phosphonobutanoic acid | - |
Rattus norvegicus | |
| 1.4 | - |
2-amino-4-[(phosphonomethyl)sulfonyl]butanoic acid | - |
Ovis aries | |
| 1.42 | - |
2-amino-4-hydroxyglutaric acid | - |
Chlorella sp. | |
| 1.8 | - |
3-[(diphosphonomethyl)amino]benzoic acid | - |
Oryza sativa | |
| 2.1 | - |
(1-amino-4-methoxy-4-oxobutyl)phosphonic acid | - |
Rattus norvegicus | |
| 2.2 | - |
2-amino-4-[methyl(phosphonomethyl)phosphoryl]butanoic acid | - |
Pisum sativum | |
| 3 | - |
L-glutamyl gamma-phosphinic acid | - |
Columba sp. | |
| 3.4 | - |
(2R,3S)-3-aminooxetane-2-carboxylic acid | plastidic isozyme | Spinacia oleracea | |
| 4 | - |
(2S)-2-amino-4-[hydroxy(nitroso)amino]butanoic acid | - |
Mus musculus | |
| 4.47 | - |
([[2-(4-hydroxyphenyl)ethyl]amino]methanediyl)bis(phosphonic acid) | - |
Oryza sativa | |
| 4.8 | - |
5-oxo-6-phosphononorleucine | - |
Escherichia coli | |
| 5 | - |
methionine sulfoxide | above | Escherichia coli | |
| 5.5 | - |
(1,4-diamino-4-oxobutyl)phosphonic acid | - |
Rattus norvegicus | |
| 6.2 | - |
(3,4-diamino-4-oxobutyl)methylphosphinic acid | - |
Rattus norvegicus | |
| 6.3 | - |
4-phosphonoisovaline | - |
Rattus norvegicus | |
| 8.7 | - |
(3-amino-4-methoxy-4-oxobutyl)methylphosphinic acid | - |
Rattus norvegicus | |
| 9.5 | - |
4-amino-4-[hydroxy(methyl)phosphoryl]pentanoic acid | - |
Rattus norvegicus | |
| 16 | - |
4-amino-4-phosphonopentanoic acid | - |
Rattus norvegicus | |
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