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Literature summary for 3.4.24.3 extracted from
- Purification and separation of individual collagenases of Clostridium histolyticum using red dye ligand chromatography (1984), Biochemistry, 23, 3077-3085.
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Collagen + H2O | Hathewaya histolytica | degradation of helical regions of native collagen to small fragments, preferential cleavage: -Gly in the sequence Pro-Xaa-Gly-Pro | ? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Hathewaya histolytica | - |
6 forms: alpha, beta, gamma, delta, epsilon, zeta differ in substrate specificity | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Hathewaya histolytica |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| culture filtrate | - |
Hathewaya histolytica | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 2-furanacryloyl-Leu-Gly-Pro-Ala + H2O | - |
Hathewaya histolytica | 2-furanacryloyl-Leu + Gly-Pro-Ala | - |
? | |
| Collagen + H2O | degradation of helical regions of native collagen to small fragments, preferential cleavage: -Gly in the sequence-Pro-Xaa-Gly-Pro, nondenatured triple helical form | Hathewaya histolytica | Hydrolyzed collagen | - |
? | |
| Collagen + H2O | degradation of helical regions of native collagen to small fragments, preferential cleavage: -Gly in the sequence Pro-Xaa-Gly-Pro | Hathewaya histolytica | ? | - |
? | |
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