Application | Comment | Organism |
---|---|---|
medicine | role in the invasive and metastatic progression of gastric carcinoma, tendency towards a worse prognosis in patients whose tumors exhibit high levels of the 170000 Da seprase dimer | Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
97000 | - |
Western immunoblotting, monomer | Homo sapiens |
170000 | - |
Western immunoblotting, dimer | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
endothelial cell | weakly located in microvessel endothelial cells | Homo sapiens | - |
fibroblast | - |
Homo sapiens | - |
gastric cancer cell | mainly located, seprase-expressing carcinoma tissue more often found in the scirrhous type than in other types of gastric carcinoma | Homo sapiens | - |
additional information | absent in normal tissue | Homo sapiens | - |
stromal cell | weakly located | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Gelatin + H2O | seprase-dimer | Homo sapiens | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
dimer | Western immunoblotting, 76% expression frequency | Homo sapiens |
monomer | Western immunoblotting | Homo sapiens |
Synonyms | Comment | Organism |
---|---|---|
seprase | - |
Homo sapiens |
type II transmembrane serine protease | - |
Homo sapiens |