Literature summary for 3.4.21.122 extracted from

Schuler, B.A.; Habermann, A.C.; Plosa, E.J.; Taylor, C.J.; Jetter, C.; Negretti, N.M.; Kapp, M.E.; Benjamin, J.T.; Gulleman, P.; Nichols, D.S.; Braunstein, L.Z.; Hackett, A.; Koval, M.; Guttentag, S.H.; Blackwell, T.S.; Webber, S.A.; Banovich, N.E.; Banovich, N.E.; Banovich, N.E.; Kropski, J.A.; Sucre, J.M.
Age-determined expression of priming protease TMPRSS2 and localization of SARS-CoV-2 in lung epithelium (2021), J. Clin. Invest., 131, e140766 .

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	C9JKZ3	-	-
Mus musculus	-	-	-

Source Tissue	Comment	Organism	Textmining
alveolar epithelial cell line	expression is highest in ciliated cells and type I alveolar epithelial cells (AT1)	Homo sapiens	-

Synonyms	Comment	Organism
TMPRSS2	-	Mus musculus
TMPRSS2	-	Homo sapiens

Organism	Comment	Expression
Mus musculus	TMPRSS2 expression is increased during alveolarization into adulthood	up
Homo sapiens	TMPRSS2 expression is increased during alveolarization into adulthood	up

General Information	Comment	Organism
physiological function	TMPRSS2 is the canonical protease mediating cellular entry for coronaviruses, including SARS-CoV-2	Mus musculus

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Release 2023.1 (January 2023)