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Literature summary for 3.4.21.122 extracted from

  • Abe, M.; Tahara, M.; Sakai, K.; Yamaguchi, H.; Kanou, K.; Shirato, K.; Kawase, M.; Noda, M.; Kimura, H.; Matsuyama, S.; Fukuhara, H.; Mizuta, K.; Maenaka, K.; Ami, Y.; Esumi, M.; Kato, A.; Takeda, M.
    TMPRSS2 is an activating protease for respiratory parainfluenza viruses (2013), J. Virol., 87, 11930-11935 .
    View publication on PubMedView publication on EuropePMC
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Cloned(Commentary)

Cloned (Comment) Organism
expression in Vero cell Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens O15393
-
-

Source Tissue

Source Tissue Comment Organism Textmining
Calu-3 cell
-
 Homo sapiens
-
Huh-7 cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
human parainfluenza virus F-protein + H2O
-
 Homo sapiens ?
-
 ?
additional information the membrane fusion proteins of respiratory viruses often possess serine and glutamine residues at the P2 and P3 positions, respectively. These residues are not critical for cleavage by TMPRSS2 Homo sapiens ?
-
 ?