Inhibitors | Comment | Organism | Structure |
---|---|---|---|
BAY 73-6691 | specific PDE9A inhibitor | Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
72000 | - |
PDE9, SDS-PAGE | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Homo sapiens | - |
colon | low gene expression | Homo sapiens | - |
erythroid cell | - |
Homo sapiens | - |
heart | low gene expression | Homo sapiens | - |
K-562 cell | - |
Homo sapiens | - |
kidney | low gene expression | Homo sapiens | - |
liver | low gene expression | Homo sapiens | - |
lung | low gene expression | Homo sapiens | - |
additional information | not detected in lymph node, mammary gland, ovary, skeletal muscle, testicle, and uterus | Homo sapiens | - |
neutrophil | PFE9A gene expression is higher in neutrophils from sickle cell disease individuals compared to control cells | Homo sapiens | - |
reticulocyte | PFE9A gene expression is higher in reticulocytes from sickle cell disease individuals compared to control cells | Homo sapiens | - |
skin | low gene expression | Homo sapiens | - |
spleen | low gene expression | Homo sapiens | - |
T-98G cell | low gene expression | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
3',5'-cGMP + H2O | - |
Homo sapiens | 5'-GMP | - |
? |
Synonyms | Comment | Organism |
---|---|---|
cGMP-specific phosphodiesterase | - |
Homo sapiens |
PDE9A | - |
Homo sapiens |