Inhibitors | Comment | Organism | Structure |
---|---|---|---|
amyloid beta protein | pathophysiological concentrations of amyloid beta proteins directly inhibit. Abeta25-35 inhibits in a non-competitive manner. Inhibition by 10 nM Abeta25-35 is reversible | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + 1-phosphatidyl-1D-myo-inositol | Homo sapiens | plasma membrane PI4KII is a target of amyloid beta proteins in the pathogenesis of Alzheimers disease | ADP + 1-phosphatidyl-1D-myo-inositol 4-phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
recombinant | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + 1-phosphatidyl-1D-myo-inositol | plasma membrane PI4KII is a target of amyloid beta proteins in the pathogenesis of Alzheimers disease | Homo sapiens | ADP + 1-phosphatidyl-1D-myo-inositol 4-phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
PI4KII | - |
Homo sapiens |
type II phosphatidylinositol 4-kinase | - |
Homo sapiens |