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Literature summary for 2.7.1.3 extracted from

  • Hayasaki, T.; Ishimoto, T.; Doke, T.; Hirayama, A.; Soga, T.; Furuhashi, K.; Kato, N.; Kosugi, T.; Tsuboi, N.; Lanaspa, M.A.; Johnson, R.J.; Maruyama, S.; Kadomatsu, K.
    Fructose increases the activity of sodium hydrogen exchanger in renal proximal tubules that is dependent on ketohexokinase (2019), J. Nutr. Biochem., 71, 54-62 .
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Mus musculus P97328
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-

Synonyms

Synonyms Comment Organism
fructokinase
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Mus musculus
ketohexokinase
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Mus musculus
KHK
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Mus musculus

General Information

General Information Comment Organism
metabolism fructose metabolism by ketohexokinase increases sodium hydrogen exchanger activity in renal proximal tubular cells via decreased intracellular cAMP level, resulting in increased renal sodium reabsorption and blood pressure in mice Mus musculus