Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | enzyme synthesis is stimulated by a hyperosmotic shock | Saccharomyces cerevisiae | |
additional information | enzyme synthesis is stimulated by a hyperosmotic shock | Schizosaccharomyces pombe |
Protein Variants | Comment | Organism |
---|---|---|
additional information | enzyme defect leads to enlarged vacuoles that do not acidify correctly, the defect can be complemented by enzyme overexpression, mutants grow poorly at elevated temperature | Saccharomyces cerevisiae |
additional information | enzyme defect leads to enlarged vacuoles that do not acidify correctly, the defect can be complemented by enzyme overexpression, mutants grow poorly at elevated temperature | Schizosaccharomyces pombe |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + 1-phosphatidyl-1D-myo-inositol 3-phosphate | Saccharomyces cerevisiae | reaction is essential for retrograde trafficking between the vacuole/lysosome and the late endosome and also for trafficking of some proteins into the vacuole via multivesicular bodies, enzyme synthesis is regulated by vac14 and vac7, 2 upstream activators, physiological roles of the enzyme and regulation mechnaism, overview | ADP + 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate | - |
? | |
ATP + 1-phosphatidyl-1D-myo-inositol 3-phosphate | Schizosaccharomyces pombe | reaction is essential for retrograde trafficking between the vacuole/lysosome and the late endosome and also for trafficking of some proteins into the vacuole via multivesicular bodies, enzyme synthesis is regulated by vac14 and vac7, 2 upstream activators, physiological roles of the enzyme and regulation mechnaism, overview | ADP + 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Saccharomyces cerevisiae | - |
- |
- |
Schizosaccharomyces pombe | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + 1-phosphatidyl-1D-myo-inositol 3-phosphate | - |
Saccharomyces cerevisiae | ADP + 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate | - |
? | |
ATP + 1-phosphatidyl-1D-myo-inositol 3-phosphate | - |
Schizosaccharomyces pombe | ADP + 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate | - |
? | |
ATP + 1-phosphatidyl-1D-myo-inositol 3-phosphate | reaction is essential for retrograde trafficking between the vacuole/lysosome and the late endosome and also for trafficking of some proteins into the vacuole via multivesicular bodies, enzyme synthesis is regulated by vac14 and vac7, 2 upstream activators, physiological roles of the enzyme and regulation mechnaism, overview | Saccharomyces cerevisiae | ADP + 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate | - |
? | |
ATP + 1-phosphatidyl-1D-myo-inositol 3-phosphate | reaction is essential for retrograde trafficking between the vacuole/lysosome and the late endosome and also for trafficking of some proteins into the vacuole via multivesicular bodies, enzyme synthesis is regulated by vac14 and vac7, 2 upstream activators, physiological roles of the enzyme and regulation mechnaism, overview | Schizosaccharomyces pombe | ADP + 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Fab1 | - |
Saccharomyces cerevisiae |
Fab1 | - |
Schizosaccharomyces pombe |
PtdIns3P 5-kinase | - |
Saccharomyces cerevisiae |
PtdIns3P 5-kinase | - |
Schizosaccharomyces pombe |