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Literature summary for 2.5.1.120 extracted from

  • Joshi, S.; Mahanta, N.; Fedoseyenko, D.; Williams, H.; Begley, T.P.
    Aminofutalosine synthase Evidence for captodative and aryl radical intermediates using beta-scission and SRN1 trapping reactions (2017), J. Am. Chem. Soc., 139, 10952-10955 .
    View publication on PubMed
Search for more literature for 2.5.1.120

Activating Compound

Activating Compound Comment Organism Structure
Dithionite
-
 Thermus thermophilus

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli Thermus thermophilus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0133
-
 S-adenosyl-L-methionine at pH 7.5 and 25°C Thermus thermophilus
0.335
-
 3-[(1-carboxyvinyl)oxy]benzoate at pH 7.5 and 25°C Thermus thermophilus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
S-adenosyl-L-methionine + 3-[(1-carboxyvinyl)oxy]benzoate + H2O Thermus thermophilus
-
 6-amino-6-deoxyfutalosine + L-methionine + HCO3-
-
 ?

Organism

Organism UniProt Comment Textmining
Thermus thermophilus
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-adenosyl-L-methionine + 3-[(1-carboxyvinyl)oxy]benzoate + H2O
-
 Thermus thermophilus 6-amino-6-deoxyfutalosine + L-methionine + HCO3-
-
 ?
S-adenosyl-L-methionine + 3-[(3-amino-3-oxoprop-1-en-2-yl)oxy]benzoic acid + H2O
-
 Thermus thermophilus 5'-deoxy-5'-(4-(4-carboxyphenoxy)-4-carboxybutyl)adenosine + ?
-
 ?
S-adenosyl-L-methionine + 3-[[(Z)-2-bromo-1-carboxyethenyl]oxy]benzoic acid + H2O
-
 Thermus thermophilus 9-[(6E)-7-O-(3-carboxyphenyl)-5,6-dideoxy-beta-D-ribo-oct-6-enofuranuronosyl]adenine + 9-[6-(bromomethylidene)-5,6-dideoxy-beta-D-ribo-heptofuranuronosyl]adenine + ?
-
 ?
S-adenosyl-L-methionine + 4-bromo-3-[(1-carboxyethenyl)oxy]benzoic acid + H2O
-
 Thermus thermophilus 9-[8-(3-carboxyphenyl)-5,6,7-trideoxy-beta-D-ribo-octodialdo-1,4-furanosyl]adenine + 9-[8-(2-bromo-5-carboxyphenyl)-5,6,7-trideoxy-beta-D-ribo-octodialdo-1,4-furanosyl]adenine + ?
-
 ?

Synonyms

Synonyms Comment Organism
MqnE
-
 Thermus thermophilus

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
0.0037
-
 3-[(1-carboxyvinyl)oxy]benzoate at pH 7.5 and 25°C Thermus thermophilus

Cofactor

Cofactor Comment Organism Structure
S-adenosyl-L-methionine
-
 Thermus thermophilus
[4Fe-4S]-center
-
 Thermus thermophilus