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Literature summary for 2.4.3.2 extracted from

  • Pan, Y.; Hu, J.; Ma, J.; Qi, X.; Zhou, H.; Miao, X.; Zheng, W.; Jia, L.
    MiR-193a-3p and miR-224 mediate renal cell carcinoma progression by targeting alpha-2,3-sialyltransferase IV and the phosphatidylinositol 3 kinase/Akt pathway (2018), Mol. Carcinog., 57, 1067-1077 .
    View publication on PubMed
Search for more literature for 2.4.3.2

Inhibitors

Inhibitors Comment Organism Structure
miR-193a-3p directly inhibits isoform ST3GalIV Homo sapiens
miR-224 directly inhibits isoform ST3GalIV Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
CMP-N-acetyl-beta-neuraminate + a beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-R Homo sapiens
-
 CMP + an N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-R
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens Q11206
-
-

Source Tissue

Source Tissue Comment Organism Textmining
ACHN cell
-
 Homo sapiens
-
HK-2 cell
-
 Homo sapiens
-
kidney
-
 Homo sapiens
-
RCC 786-O cell
-
 Homo sapiens
-
renal cell carcinoma cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
CMP-N-acetyl-beta-neuraminate + a beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-R
-
 Homo sapiens CMP + an N-acetyl-alpha-neuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminyl-R
-
 ?

Synonyms

Synonyms Comment Organism
alpha-2,3-sialyltransferase IV
-
 Homo sapiens
ST3GalIV isoform Homo sapiens