Protein Variants | Comment | Organism |
---|---|---|
additional information | construcution of N-terminal deletion mutants. The N-terminal region of RNF2, including the RING finger domain, is essential for the protein-protein interaction with E2 enzymes | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q99496 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-ubiquitinyl-[Hip2]-L-cysteine + [acceptor protein]-L-lysine | - |
Homo sapiens | [Hip2]-L-cysteine + N6-ubiquitinyl-[acceptor protein]-L-lysine | isoform RNF2 interacts with E2 protein Hip2, i.e. Huntingtin-interacting protein-2, and with Ubc4, UbcH5. RNF2 shows ubiquitin transferase E3 activity in the presence of Hip2 | ? |
Synonyms | Comment | Organism |
---|---|---|
RNF2 | - |
Homo sapiens |