Inhibitors | Comment | Organism | Structure |
---|---|---|---|
R283 | specific inhibitor, i.e. 1,3-dimethyl-2-[(2-oxopropyl)thio]imidazolium chloride, complete inhibition at 0.25 mM | Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
80000 | - |
x * 80000, SDS-PAGE | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
monocyte | - |
Homo sapiens | - |
THP-1 cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
[protein]-gamma-glutamine + 5-(biotinamido) pentylamine | - |
Homo sapiens | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 80000, SDS-PAGE | Homo sapiens |
Synonyms | Comment | Organism |
---|---|---|
TG2 | - |
Homo sapiens |
transglutaminase 2 | - |
Homo sapiens |
Organism | Comment | Expression |
---|---|---|
Homo sapiens | the enzyme plays a key role in homocysteine-induced activation of THP-1 monocytes, involving oxidative as well as endoplasmic resticulum stress and inflammation | up |
General Information | Comment | Organism |
---|---|---|
physiological function | transglutaminase 2 is involved in homocysteine-induced activation of human THP-1 monocytes | Homo sapiens |