Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1-(1-benzothiophen-2-yl)-3-[benzyl(tert-butyl)amino]propan-1-one | - |
Cavia porcellus | |
1-(furan-2-yl)-3-[(2-hydroxyethyl)(propan-2-yl)amino]propan-1-one | - |
Cavia porcellus | |
3-[benzyl(ethyl)amino]-1-(5-chlorothiophen-2-yl)propan-1-one | - |
Cavia porcellus | |
3-[benzyl(propan-2-yl)amino]-1-(5-bromothiophen-2-yl)propan-1-one | - |
Cavia porcellus | |
3-[benzyl(propan-2-yl)amino]-1-(5-chlorothiophen-2-yl)propan-1-one | - |
Cavia porcellus | |
3-[benzyl(tert-butyl)amino]-1-(4-nitrophenyl)propan-1-one | - |
Cavia porcellus | |
3-[benzyl(tert-butyl)amino]-1-(5-bromothiophen-2-yl)propan-1-one | - |
Cavia porcellus | |
3-[benzyl(tert-butyl)amino]-1-(5-chlorothiophen-2-yl)propan-1-one | - |
Cavia porcellus | |
3-[benzyl(tert-butyl)amino]-1-(thiophen-2-yl)propan-1-one | - |
Cavia porcellus | |
3-[bis(2-hydroxyethyl)amino]-1-(furan-2-yl)propan-1-one | - |
Cavia porcellus | |
additional information | beta-aminoethyl ketones strongly inhibit TGase, alpha- and gamma-aminoalkyl ketones show very weak TGase inhibition | Cavia porcellus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Cavia porcellus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Cavia porcellus | - |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.000081 | - |
pH 7.5 | Cavia porcellus | 3-[benzyl(tert-butyl)amino]-1-(5-bromothiophen-2-yl)propan-1-one | |
0.0001 | - |
pH 7.5 | Cavia porcellus | 3-[benzyl(tert-butyl)amino]-1-(5-chlorothiophen-2-yl)propan-1-one | |
0.00012 | - |
pH 7.5 | Cavia porcellus | 1-(furan-2-yl)-3-[(2-hydroxyethyl)(propan-2-yl)amino]propan-1-one | |
0.00017 | - |
pH 7.5 | Cavia porcellus | 3-[benzyl(tert-butyl)amino]-1-(4-nitrophenyl)propan-1-one | |
0.00019 | - |
pH 7.5 | Cavia porcellus | 3-[benzyl(propan-2-yl)amino]-1-(5-bromothiophen-2-yl)propan-1-one | |
0.00021 | - |
pH 7.5 | Cavia porcellus | 1-(1-benzothiophen-2-yl)-3-[benzyl(tert-butyl)amino]propan-1-one | |
0.00023 | - |
pH 7.5 | Cavia porcellus | 3-[benzyl(propan-2-yl)amino]-1-(5-chlorothiophen-2-yl)propan-1-one | |
0.00036 | - |
pH 7.5 | Cavia porcellus | 3-[bis(2-hydroxyethyl)amino]-1-(furan-2-yl)propan-1-one | |
0.00042 | - |
pH 7.5 | Cavia porcellus | 3-[benzyl(ethyl)amino]-1-(5-chlorothiophen-2-yl)propan-1-one | |
0.00044 | - |
pH 7.5 | Cavia porcellus | 3-[benzyl(tert-butyl)amino]-1-(thiophen-2-yl)propan-1-one |