Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2-([3-(2-chlorophenyl)-4-oxo-5-phenyl-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl]thio)acetohydrazide | 50% inhibition at 0.0015 mM, standard format | Homo sapiens | |
2-([3-(2-fluorophenyl)-4-oxo-5-phenyl-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl]thio)acetohydrazide | 50% inhibition at 0.00025 mM, standard format, at 0.00018 mM, full progress curve | Homo sapiens | |
2-([3-(2-methoxyphenyl)-4-oxo-5-phenyl-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl]thio)acetohydrazide | 50% inhibition at 0.00082 mM, standard format, at 0.00047 mM, full progress curve | Homo sapiens | |
2-([3-(3-chlorophenyl)-4-oxo-5-phenyl-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl]thio)acetohydrazide | 50% inhibition at 0.0018 mM, standard format | Homo sapiens | |
2-([3-(3-fluorophenyl)-4-oxo-3,4,5,6,7,8-hexahydro[1]benzothieno[2,3-d]pyrimidin-2-yl]thio)acetohydrazide | 50% inhibition at 0.00045 mM, full progress curve | Homo sapiens | |
2-([3-(3-fluorophenyl)-4-oxo-5-phenyl-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl]thio)acetohydrazide | 50% inhibition at 0.00021 mM, standard format, at 0.00014 mM, full progress curve | Homo sapiens | |
2-([3-(3-fluorophenyl)-5-(2-hydroxyphenyl)-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl]thio)acetohydrazide | 50% inhibition at 0.0008 mM, standard format, at 0.00025 mM, full progress curve | Homo sapiens | |
2-([3-(3-fluorophenyl)-5-(3-methoxyphenyl)-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl]thio)acetohydrazide | 50% inhibition at 0.0014 mM, standard format | Homo sapiens | |
2-([3-(3-fluorophenyl)-5-methyl-4-oxo-3,4,5,6,7,8-hexahydro[1]benzothieno[2,3-d]pyrimidin-2-yl]thio)acetohydrazide | 50% inhibition at 0.0002 mM, full progress curve | Homo sapiens | |
2-([3-(3-fluorophenyl)-5-phenyl-4-oxo-3,4,5,6,7,8-hexahydro[1]benzothieno[2,3-d]pyrimidin-2-yl]thio)acetohydrazide | 50% inhibition at 0.00093 mM, standard format, at 0.00071 mM, full progress curve | Homo sapiens | |
2-([3-(3-fluorophenyl)-7-methyl-4-oxo-3,4,5,6,7,8-hexahydropyrido[4',3':4,5]thieno[2,3-d]pyrimidin-2-yl]thio)acetohydrazide | 50% inhibition at 0.00053 mM, full progress curve | Homo sapiens | |
2-([3-(3-methoxyphenyl)-4-oxo-5-phenyl-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl]thio)acetohydrazide | 50% inhibition at 0.0021 mM, standard format | Homo sapiens | |
2-([3-(4-chlorophenyl)-4-oxo-5-phenyl-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl]thio)acetohydrazide | 50% inhibition at 0.0005 mM, standard format, at 0.00016 mM, full progress curve | Homo sapiens | |
2-([3-(4-methoxyphenyl)-4-oxo-5-phenyl-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl]thio)acetohydrazide | 50% inhibition at 0.0018 mM, standard format | Homo sapiens | |
2-([5-(4-fluorophenyl)-4-oxo-3-phenyl-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl]thio)acetohydrazide | 50% inhibition at 0.0008 mM, standard format, at 0.00029 mM, full progress curve | Homo sapiens | |
2-[(3-amino-2-oxopropyl)thio]-3-(3-fluorophenyl)-5-phenylthieno[2,3-d]pyrimidin-4(3H)-one | 50% inhibition at 0.0053 mM, standard format | Homo sapiens | |
2-[(3-benzyl-4-oxo-5-phenyl-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)thio]acetohydrazide | 50% inhibition at 0.0012 mM, standard format, at 0.00048 mM, full progress curve | Homo sapiens | |
2-[(3-methyl-4-oxo-5-phenyl-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)thio]acetohydrazide | 50% inhibition at 0.0023 mM, standard format | Homo sapiens | |
2-[(4-oxo-3,5-diphenyl-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)amino]acetohydrazide | 50% inhibition at 0.0037 mM, full progress curve | Homo sapiens | |
2-[(4-oxo-3,5-diphenyl-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)oxy]acetohydrazide | 50% inhibition at 0.0045 mM, standard format | Homo sapiens | |
2-[(4-oxo-3,5-diphenyl-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)thio]acetohydrazide | 50% inhibition at 0.0008 mM, standard format, at 0.00025 mM, full progress curve | Homo sapiens | |
2-[(4-oxo-5-phenyl-3-pyridin-3-yl-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)thio]acetohydrazide | 50% inhibition at 0.002 mM, standard format | Homo sapiens | |
2-[(6-methyl-4-oxo-3,5-diphenyl-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)thio]acetohydrazide | 50% inhibition at 0.0015 mM, standard format, at 0.00016 mM, full progress curve | Homo sapiens | |
3-[(6-methyl-4-oxo-3,5-diphenyl-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)thio]propanohydrazide | 50% inhibition at 0.0013 mM, standard format | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
alpha-N-t-butyloxycarbonyl-L-Lys-CH2-CH2-dansyl + N,N-dimethylcasein | - |
Homo sapiens | ? | - |
? |