Application | Comment | Organism |
---|---|---|
medicine | knock-down of enzymeby lentiviral shRNA reduces the invasion potential of MDA-MB-231 cells. Enzymic activity may be important in breast cancer growth and metastasis | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(5Z)-5-(2-hydroxybenzylidene)-2-thioxo-1,3-thiazolidin-4-one | i.e. Rhod-o-hp. Significant reduction of cell growth by increasing the percent of MDA-MB-231 cells in G2/M phase of the cell cycle, and reduction of the ability of cells to grow in soft agar | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
MDA-MB-231 cell | - |
Homo sapiens | - |
General Information | Comment | Organism |
---|---|---|
physiological function | knock-down of enzyme by lentiviral shRNA reduces the invasion potential of MDA-MB-231 cells. Enzymic activity may be important in breast cancer growth and metastasis | Homo sapiens |