Application | Comment | Organism |
---|---|---|
diagnostics | important role for the CerS genes in breast cancer etiology or diagnosis, overview | Homo sapiens |
Cloned (Comment) | Organism |
---|---|
gene CERS4, isozyme expression analysis | Homo sapiens |
gene CERS6, isozyme expression analysis | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q6ZMG9 | - |
- |
Homo sapiens | Q9HA82 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
breast cancer cell | isozymes CerS2 (EC 2.3.1.297) and CerS6 (EC 2.3.1.24) mRNA is significantly elevated in breast cancer tissue compared to normal tissue, with approximately half of the individuals showing elevated CerS2 and CerS6 mRNA. A significant correlation is found between CerS2 and CerS6 isozyme expression, and between isozymes CerS4 (EC 2.3.1.24) and CerS2/CerS6 expression | Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
ceramide synthase 4 | - |
Homo sapiens |
ceramide synthase 6 | - |
Homo sapiens |
CerS4 | - |
Homo sapiens |
CerS6 | - |
Homo sapiens |