Cloned (Comment) | Organism |
---|---|
three different splicing isoforms, OTC-t1, OTC-t2, and OTC-t3, all three isoforms use a canonical AAUAAA hexamer that is predicted to fold into a hairpin secondary structure which might be exposed to the cleavage and polyadenylation specificity factor. In addition, the OTC-t1 and OTC-t2 transcripts display heterogeneity at the cleavage sites in a tissue-dependent manner. Secondary structure of the OTC mRNA polyA signals, overview | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P00480 | mRNA isoforms OTC-t1, OTC-t2, and OTC-t3 are transcribed from the OTC gene | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | OTC-t3 | Homo sapiens | - |
liver | - |
Homo sapiens | - |
additional information | two major transcripts, OTC-t1 and OTC-t2, are more highly expressed than any of the other isoforms in all the tissues analyzed | Homo sapiens | - |
skeletal muscle | - |
Homo sapiens | - |
small intestine | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | OTC-t1 and OTC-t2 transcripts display heterogeneity at the cleavage sites in a tissue-dependent manner | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ornithine transcarbamylase | - |
Homo sapiens |
ornithine transcarbamylase 3 | - |
Homo sapiens |
OTC | - |
Homo sapiens |