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Literature summary for 2.1.1.319 extracted from

  • Adamopoulos, P.G.; Mavrogiannis, A.V.; Kontos, C.K.; Scorilas, A.
    Novel alternative splice variants of the human protein arginine methyltransferase 1 (PRMT1) gene, discovered using next-generation sequencing (2019), Gene, 699, 135-144 .
    View publication on PubMed

Application

Application Comment Organism
medicine splive variant PRMT1 v.2 promotes the survival and invasiveness of breast cancer cells, while it could serve as a biomarker of unfavorable prognosis in colon cancer patients Homo sapiens

Cloned(Commentary)

Cloned (Comment) Organism
molecular cloning of alternative splice variants of PRMT1 with the use of 3' RACE coupled with next-generation sequencing technology. 58 PRMT1 transcripts are identified, 34 of which are mRNAs encoding protein isoforms, whereas the rest 24 transcripts are candidates for nonsense-mediated mRNA decay Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens Q99873
-
-

Source Tissue

Source Tissue Comment Organism Textmining
A-549 cell
-
Homo sapiens
-
ACHN cell
-
Homo sapiens
-
AGS cell
-
Homo sapiens
-
BT-20 cell
-
Homo sapiens
-
BT-474 cell
-
Homo sapiens
-
Caco-2 cell
-
Homo sapiens
-
Caki-1 cell
-
Homo sapiens
-
Colo-205 cell
-
Homo sapiens
-
D-54MG cell
-
Homo sapiens
-
DAUDI cell
-
Homo sapiens
-
DLD-1 cell
-
Homo sapiens
-
DU-145 cell
-
Homo sapiens
-
ES-2 cell
-
Homo sapiens
-
FM3A cell
-
Homo sapiens
-
HCT-116 cell
-
Homo sapiens
-
HEK-293 cell
-
Homo sapiens
-
HeLa cell
-
Homo sapiens
-
Hep-G2 cell
-
Homo sapiens
-
HL-60 cell
-
Homo sapiens
-
HT-29 cell
-
Homo sapiens
-
Huh-7 cell
-
Homo sapiens
-
Ishikawa cell
-
Homo sapiens
-
JURKAT cell
-
Homo sapiens
-
K-562 cell
-
Homo sapiens
-
LNCaP cell
-
Homo sapiens
-
MCF-7 cell
-
Homo sapiens
-
MDA-MB-231 cell
-
Homo sapiens
-
MDA-MB-468 cell
-
Homo sapiens
-
MDAH-2774 cell
-
Homo sapiens
-
OVCAR-3 cell
-
Homo sapiens
-
PC-3 cell
-
Homo sapiens
-
RAJI cell
-
Homo sapiens
-
RCC 786-O cell
-
Homo sapiens
-
REC-1 cell
-
Homo sapiens
-
RKO cell
-
Homo sapiens
-
RT-4 cell
-
Homo sapiens
-
SH-SY5Y cell
-
Homo sapiens
-
SiHa cell
-
Homo sapiens
-
SK-BR-3 cell
-
Homo sapiens
-
SK-UT-1B cell
-
Homo sapiens
-
SKOV-3 cell
-
Homo sapiens
-
SU-DHL-1 cell
-
Homo sapiens
-
SW-620 cell
-
Homo sapiens
-
T-24 cell
-
Homo sapiens
-
T-47D cell
-
Homo sapiens
-
U-251MG cell
-
Homo sapiens
-
U-87MG cell
-
Homo sapiens
-
U-937 cell
-
Homo sapiens
-
ZR-75-1 cell
-
Homo sapiens
-

Synonyms

Synonyms Comment Organism
PRMT1
-
Homo sapiens
protein arginine methyltransferase 1
-
Homo sapiens

Expression

Organism Comment Expression
Homo sapiens two splice variants of PRMT1 (variants v.1 and v.2) are downregulated in breast cancer down

General Information

General Information Comment Organism
physiological function the enzyme is involved in a variety of processes including transcription, DNA repair, and signal transduction Homo sapiens