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Literature summary for 2.1.1.2 extracted from

  • Tachikawa, M.; Watanabe, M.; Fukaya, M.; Sakai, K.; Terasaki, T.; Hosoya, K.I.
    Cell-type-specific spatiotemporal expression of creatine biosynthetic enzyme S-adenosylmethionine guanidinoacetate N-methyltransferase in developing mouse brain (2018), Neurochem. Res., 43, 500-510 .
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Mus musculus O35969
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Source Tissue

Source Tissue Comment Organism Textmining
astrocyte moderate expression levels throughout development Mus musculus
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brain two waves of high GAMT expression. The first involves high expression in mitotic cells in the ventricular zone of the brain wall and the external granular layer of the cerebellum at the embryonic and neonatal stages. The second is initiated by striking up-regulation of GAMT in oligodendrocytes during the second and third postnatal weeks and continues to adulthood Mus musculus
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neuron GAMT levels are low to moderate in neuroblasts residing in the ventricular zone, increase during the second postnatal week, and decrease to very low levels thereafter Mus musculus
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oligodendrocyte striking up-regulation of GAMT in oligodendrocytes during the second and third postnatal weeks, expression continues to adulthood Mus musculus
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pericyte GAMT is highly expressed in perivascular pericytes and smooth muscle cells after birth Mus musculus
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smooth muscle GAMT was highly expressed in perivascular pericytes and smooth muscle cells after birth Mus musculus
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Synonyms

Synonyms Comment Organism
GAMT
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Mus musculus