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Literature summary for 1.8.4.11 extracted from

  • Yang, J.; Wen, Y.; Peng, L.; Chen, Y.; Cheng, X.; Chen, Y.
    Identification of MsrA homologues for the preparation of (R)-sulfoxides at high substrate concentrations (2019), Org. Biomol. Chem., 17, 3381-3388 .
    View publication on PubMed
Search for more literature for 1.8.4.11

Application

Application Comment Organism
synthesis the study supports that the asymmetric reductive resolution of rac-sulfoxides using MsrA would become an effective strategy for the green synthesis of optically pure sulfoxides Pseudomonas alcaliphila

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli BL21(DE3) Pseudomonas alcaliphila

Organism

Organism UniProt Comment Textmining
Pseudomonas alcaliphila
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
racemic (ethanesulfinyl)benzene + dithiothreitol specifically reduces the (S)-enantiomer of methionine sulfoxide to methionine Pseudomonas alcaliphila (ethylsulfanyl)benzene + [(R)-ethanesulfinyl]benzene + dithiothreitol disulfide + H2O
-
 ?
racemic (methanesulfinyl)benzene + dithiothreitol specifically reduces the (S)-enantiomer of methionine sulfoxide to methionine Pseudomonas alcaliphila (methylsulfanyl)benzene + [(R)-methanesulfinyl]benzene + dithiothreitol disulfide + H2O
-
 ?
racemic 1-(methanesulfinyl)-4-methylbenzene + dithiothreitol specifically reduces the (S)-enantiomer of methionine sulfoxide to methionine Pseudomonas alcaliphila 1-methyl-4-(methylsulfanyl)benzene + 1-[(R)-methanesulfinyl]-4-methylbenzene + dithiothreitol disulfide + H2O
-
 ?
racemic 1-bromo-4-(methanesulfinyl)benzene + dithiothreitol specifically reduces the (S)-enantiomer of methionine sulfoxide to methionine Pseudomonas alcaliphila 1-bromo-4-(methylsulfanyl)benzene + 1-bromo-4-[(R)-methanesulfinyl]benzene + dithiothreitol disulfide + H2O
-
 ?
racemic 1-fluoro-4-(methanesulfinyl)benzene + dithiothreitol specifically reduces the (S)-enantiomer of methionine sulfoxide to methionine Pseudomonas alcaliphila 1-fluoro-4-(methylsulfanyl)benzene + 1-fluoro-4-[(R)-methanesulfinyl]benzene + dithiothreitol disulfide + H2O
-
 ?
racemic 2-(methanesulfinyl)aniline + dithiothreitol specifically reduces the (S)-enantiomer of methionine sulfoxide to methionine Pseudomonas alcaliphila 2-(methylsulfanyl)aniline + 2-[(R)-methanesulfinyl]aniline + dithiothreitol disulfide + H2O
-
 ?
racemic 2-(methanesulfinyl)naphthalene + dithiothreitol specifically reduces the (S)-enantiomer of methionine sulfoxide to methionine Pseudomonas alcaliphila 2-(methylsulfanyl)naphthalene + 2-[(R)-methanesulfinyl]naphthalene + dithiothreitol disulfide + H2O
-
 ?
racemic 2-(methanesulfinyl)phenol + dithiothreitol specifically reduces the (S)-enantiomer of methionine sulfoxide to methionine Pseudomonas alcaliphila 2-(methylsulfanyl)phenol + 2-[(R)-methanesulfinyl]phenol + dithiothreitol disulfide + H2O
-
 ?
racemic 3-(methanesulfinyl)aniline + dithiothreitol specifically reduces the (S)-enantiomer of methionine sulfoxide to methionine Pseudomonas alcaliphila 3-(methylsulfanyl)aniline + 3-[(R)-methanesulfinyl]aniline + dithiothreitol disulfide + H2O
-
 ?
racemic 4-(methanesulfinyl)benzaldehyde + dithiothreitol specifically reduces the (S)-enantiomer of methionine sulfoxide to methionine Pseudomonas alcaliphila 4-(methylsulfanyl)benzaldehyde + 4-[(R)-methanesulfinyl]benzaldehyde + dithiothreitol disulfide + H2O
-
 ?
racemic N-[2-(methanesulfinyl)phenyl]acetamide + dithiothreitol specifically reduces the (S)-enantiomer of methionine sulfoxide to methionine Pseudomonas alcaliphila N-[2-(methylsulfanyl)phenyl]acetamide + N-(2-[(R)-methanesulfinyl]phenyl)acetamide+ dithiothreitol disulfide + H2O
-
 ?

Synonyms

Synonyms Comment Organism
MsrA
-
 Pseudomonas alcaliphila

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
30
-
-
 Pseudomonas alcaliphila

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8
-
-
 Pseudomonas alcaliphila

General Information

General Information Comment Organism
physiological function important protein repairing enzyme that protects cells from oxidative stress Pseudomonas alcaliphila