Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
23649 | - |
x * 23649, calculated from amino acid sequence | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-methionine (S)-sulfoxide + thioredoxin | Homo sapiens | the enzyme is specific for the S epimer of methionine sulfoxide | L-methionine + thioredoxin disulfide + H2O | - |
r | |
additional information | Homo sapiens | the enzyme catalyzes its own autooxidation as well as oxidation of free methionine and methionine residues in peptides and proteins | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
alpha-synuclein + dithiothreitol | alpha-synuclein is oxidized at both Met1 and Met5 but not at Met116 or Met127 | Homo sapiens | ? | - |
? | |
Gly-L-Met-Gly + dithiothreitol | - |
Homo sapiens | ? | - |
? | |
L-methionine (S)-sulfoxide + thioredoxin | the enzyme is specific for the S epimer of methionine sulfoxide | Homo sapiens | L-methionine + thioredoxin disulfide + H2O | - |
r | |
L-Pro-L-Met-L-Ala-L-Ile-L-Lys-L-Lys + dithiothreitol | - |
Homo sapiens | ? | - |
? | |
additional information | the enzyme catalyzes its own autooxidation as well as oxidation of free methionine and methionine residues in peptides and proteins | Homo sapiens | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 23649, calculated from amino acid sequence | Homo sapiens |
Synonyms | Comment | Organism |
---|---|---|
methionine sulfoxide reductase A | - |
Homo sapiens |
MsrA | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
thioredoxin | - |
Homo sapiens |