Protein Variants | Comment | Organism |
---|---|---|
C667T | high level of enzyme activity, loses almost all its activity after 20 min at 55°C, enzyme in patients with TT or TC genotype are more thermolabile than wild type enzyme at 46°C | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.026 | - |
5,10-methylenetetrahydrofolate | - |
Homo sapiens | |
0.03 | - |
NADPH | - |
Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
patients with enzyme deficiency | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
skin | - |
Homo sapiens | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
specific activity in various patients with enzyme deficiencies | Homo sapiens |
0.413 | - |
- |
Homo sapiens |
Storage Stability | Organism |
---|---|
-75°C, stable for at least 9 months in cell pellets and enzyme extracts | Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
6.3 | 6.9 | - |
Homo sapiens |