Cloned (Comment) | Organism |
---|---|
gene gapdh, recombinant expression of the Thermoanaerobacterium saccharolyticum Gapdh in Clostridium thermocellum | Thermoanaerobacterium saccharolyticum |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | a dramatic accumulation of NADH and NADPH is observed when ethanol is added to the culture. The Gapdh from Thermoanaerobacterium saccharolyticum is less sensitive to the NADH/NAD+ ratio | Thermoanaerobacterium saccharolyticum |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-glyceraldehyde 3-phosphate + phosphate + NAD(P)+ | Thermoanaerobacterium saccharolyticum | - |
3-phospho-D-glyceroyl phosphate + NAD(P)H + H+ | - |
? | |
D-glyceraldehyde 3-phosphate + phosphate + NAD(P)+ | Thermoanaerobacterium saccharolyticum DSM 8691 | - |
3-phospho-D-glyceroyl phosphate + NAD(P)H + H+ | - |
? | |
D-glyceraldehyde 3-phosphate + phosphate + NAD(P)+ | Thermoanaerobacterium saccharolyticum JW/SL-YS485 | - |
3-phospho-D-glyceroyl phosphate + NAD(P)H + H+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Thermoanaerobacterium saccharolyticum | I3VY89 | - |
- |
Thermoanaerobacterium saccharolyticum DSM 8691 | I3VY89 | - |
- |
Thermoanaerobacterium saccharolyticum JW/SL-YS485 | I3VY89 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-glyceraldehyde 3-phosphate + phosphate + NAD(P)+ | - |
Thermoanaerobacterium saccharolyticum | 3-phospho-D-glyceroyl phosphate + NAD(P)H + H+ | - |
? | |
D-glyceraldehyde 3-phosphate + phosphate + NAD(P)+ | - |
Thermoanaerobacterium saccharolyticum DSM 8691 | 3-phospho-D-glyceroyl phosphate + NAD(P)H + H+ | - |
? | |
D-glyceraldehyde 3-phosphate + phosphate + NAD(P)+ | - |
Thermoanaerobacterium saccharolyticum JW/SL-YS485 | 3-phospho-D-glyceroyl phosphate + NAD(P)H + H+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
glyceraldehyde 3-phosphate dehydrogenase | - |
Thermoanaerobacterium saccharolyticum |
Tsac_2486 | - |
Thermoanaerobacterium saccharolyticum |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
55 | - |
assay at | Thermoanaerobacterium saccharolyticum |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7 | - |
assay at | Thermoanaerobacterium saccharolyticum |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | - |
Thermoanaerobacterium saccharolyticum | |
NADP+ | - |
Thermoanaerobacterium saccharolyticum |
General Information | Comment | Organism |
---|---|---|
additional information | comparison of Gapdh protein from Clostridium thermocellum and Thermoanaerobacterium saccharolyticum, homology modeling, overview. The Gapdh from Thermoanaerobacterium saccharolyticum is less sensitive to ethanol and the NAD+/NADH ratio. Recombinant Gapdh from Thermoanaerobacterium saccharolyticum expressed in Clostridium thermocellum cells can improve the growth rate and ethanol resistance | Thermoanaerobacterium saccharolyticum |