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Literature summary for 1.14.19.77 extracted from
- Plasmanylethanolamine D1-desaturase (1992), Methods Enzymol., 209, 390-396.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| catalase | - |
Mus musculus | |
| catalase | - |
Rattus norvegicus | |
| catalase | - |
Oryctolagus cuniculus | |
| catalase | - |
Mesocricetus auratus |
General Stability
| General Stability | Organism |
|---|---|
| activity loss at -23°C, should be used freshly | Rattus norvegicus |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| CN- | be not inhibited by carbon monoxide | Mesocricetus auratus |  |
| CN- | be not inhibited by carbon monoxide | Mus musculus | |
| CN- | be not inhibited by carbon monoxide | Oryctolagus cuniculus | |
| CN- | be not inhibited by carbon monoxide | Rattus norvegicus | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| microsome | microsomal membrane, advisable to check the effect of the soluble fraction | Mus musculus | - |
- |
| microsome | microsomal membrane, advisable to check the effect of the soluble fraction | Rattus norvegicus | - |
- |
| microsome | microsomal membrane, advisable to check the effect of the soluble fraction | Oryctolagus cuniculus | - |
- |
| microsome | microsomal membrane, advisable to check the effect of the soluble fraction | Mesocricetus auratus | - |
- |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mesocricetus auratus | - |
- |
- |
| Mus musculus | - |
- |
- |
| Oryctolagus cuniculus | - |
- |
- |
| Rattus norvegicus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| ascites | - |
Mus musculus | - |
| ascites | Ehrlich cells | Rattus norvegicus | - |
| brain | - |
Rattus norvegicus | - |
| P-388D1 cell | - |
Mus musculus | - |
| sarcoma cell | Fischer R-3259 sarcoma | Rattus norvegicus | - |
| small intestine mucosa | - |
Mesocricetus auratus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | electron donors: NADPH or NADH | Mus musculus | ? | - |
? | |
| additional information | electron donors: NADPH or NADH | Rattus norvegicus | ? | - |
? | |
| additional information | electron donors: NADPH or NADH | Oryctolagus cuniculus | ? | - |
? | |
| additional information | electron donors: NADPH or NADH | Mesocricetus auratus | ? | - |
? | |
| O-1-alkyl-2-acyl-sn-glycero-3-phosphoethanolamine + electron donor + O2 | generated in situ by microsomal acylation of alkyllyso-glycero-3-phosphoethanolamine, better substrate than when it is added exogenously | Mus musculus | O-1-alk-1-enyl-2-acyl-sn-glycero-3-phosphoethanolamine + oxidized electron donor + H2O | - |
? | |
| O-1-alkyl-2-acyl-sn-glycero-3-phosphoethanolamine + electron donor + O2 | generated in situ by microsomal acylation of alkyllyso-glycero-3-phosphoethanolamine, better substrate than when it is added exogenously | Rattus norvegicus | O-1-alk-1-enyl-2-acyl-sn-glycero-3-phosphoethanolamine + oxidized electron donor + H2O | - |
? | |
| O-1-alkyl-2-acyl-sn-glycero-3-phosphoethanolamine + electron donor + O2 | generated in situ by microsomal acylation of alkyllyso-glycero-3-phosphoethanolamine, better substrate than when it is added exogenously | Oryctolagus cuniculus | O-1-alk-1-enyl-2-acyl-sn-glycero-3-phosphoethanolamine + oxidized electron donor + H2O | - |
? | |
| O-1-alkyl-2-acyl-sn-glycero-3-phosphoethanolamine + electron donor + O2 | generated in situ by microsomal acylation of alkyllyso-glycero-3-phosphoethanolamine, better substrate than when it is added exogenously | Mesocricetus auratus | O-1-alk-1-enyl-2-acyl-sn-glycero-3-phosphoethanolamine + oxidized electron donor + H2O | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| plasmanylethanolamine D1-desaturase | - |
Mus musculus |
| plasmanylethanolamine D1-desaturase | - |
Rattus norvegicus |
| plasmanylethanolamine D1-desaturase | - |
Oryctolagus cuniculus |
| plasmanylethanolamine D1-desaturase | - |
Mesocricetus auratus |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 37 | - |
- |
Mus musculus |
| 37 | - |
- |
Oryctolagus cuniculus |
| 37 | - |
enzyme assay | Rattus norvegicus |
| 37 | - |
enzyme assay | Mesocricetus auratus |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| cytochrome b5 | - |
Mus musculus | |
| cytochrome b5 | - |
Rattus norvegicus | |
| cytochrome b5 | - |
Oryctolagus cuniculus | |
| cytochrome b5 | - |
Mesocricetus auratus | |
| NADPH | or NADH | Mus musculus | |
| NADPH | or NADH | Rattus norvegicus | |
| NADPH | or NADH | Oryctolagus cuniculus | |
| NADPH | or NADH | Mesocricetus auratus | |
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Release 2023.1 (January 2023)
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