Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Metyrapone | complete inhibition at 5 mM | Rattus norvegicus | |
SKF 525 A | 75% inhibition at 0.3 mM | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Rattus norvegicus | 5739 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
endoderm | - |
Rattus norvegicus | - |
yolk sac | the enzyme is detected in the yolk sac as early as day 12 in the embryonic period and until the end of gestation | Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
1alpha,25-dihydroxyvitamin D3 + NADPH + H+ + O2 | - |
Rattus norvegicus | 1alpha,24R,25-trihydroxyvitamin D3 + NADP+ + H2O | - |
? | |
25-hydroxyvitamin D3 + NADPH + H+ + O2 | - |
Rattus norvegicus | 24R,25-dihydroxyvitamin D3 + NADP+ + H2O | - |
? |
Synonyms | Comment | Organism |
---|---|---|
1,25-(OH)2D3-24-hydroxylase | - |
Rattus norvegicus |
1,25-dihydroxyvitamin D3 24-hydroxylase | - |
Rattus norvegicus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADPH | - |
Rattus norvegicus |