Cloned (Comment) | Organism |
---|---|
Cyp7a1 expression pattern in wild-type and Cyp8b1 null mice livers, overview | Mus musculus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | - |
Mus musculus | - |
- |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
cholesterol + [reduced NADPH-hemoprotein reductase] + O2 | Mus musculus | - |
7alpha-hydroxycholesterol + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
wild-type C57Bl/6 and male Cyp8b1 knockout mice on a mixed 129Sv/Ev-C57Bl/6 background | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
hepatocyte | - |
Mus musculus | - |
liver | Cyp7a1 expression pattern in wild-type and Cyp8b1 null mice livers, Cyp7a1 expression in wild type mice shows a zonal distribution pattern, Cyp8b1 knockout mice show increased expression of Cyp7a1, overview | Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
cholesterol + [reduced NADPH-hemoprotein reductase] + O2 | - |
Mus musculus | 7alpha-hydroxycholesterol + [oxidized NADPH-hemoprotein reductase] + H2O | - |
? |
Synonyms | Comment | Organism |
---|---|---|
cholesterol 7alpha-hydroxylase | - |
Mus musculus |
CYP7A1 | - |
Mus musculus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADPH | - |
Mus musculus |