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Literature summary for 1.1.3.4 extracted from

  • Rost, D.; Welker, A.; Welker, J.; Millonig, G.; Berger, I.; Autschbach, F.; Schuppan, D.; Mueller, S.
    Liver-homing of purified glucose oxidase: A novel in vivo model of physiological hepatic oxidative stress (H(2)O(2)) (2006), J. Hepatol., 46, 482-491.
    View publication on PubMed
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Application

Application Comment Organism
analysis the enzym eis used in a model system to study physiological effects of hepatic H2O2 release on rat liver Aspergillus niger

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
D-glucose + O2 Aspergillus niger
-
 D-glucono-1,5-lactone + H2O2
-
 ?
additional information Aspergillus niger the enzyme is rapidly cleared from blood stream after application to rats, enzyme-produced H2O2 has toxic effects of rat liver and causes inflammation, at nontoxic levels it causes increased glutathione oxidation and induction of heme oxygenase 1 in the liver, overview ?
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 ?

Organism

Organism UniProt Comment Textmining
Aspergillus niger
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
D-glucose + O2
-
 Aspergillus niger D-glucono-1,5-lactone + H2O2
-
 ?
additional information the enzyme is rapidly cleared from blood stream after application to rats, enzyme-produced H2O2 has toxic effects of rat liver and causes inflammation, at nontoxic levels it causes increased glutathione oxidation and induction of heme oxygenase 1 in the liver, overview Aspergillus niger ?
-
 ?

Synonyms

Synonyms Comment Organism
GOX
-
 Aspergillus niger