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Literature summary for 1.1.3.16 extracted from

  • Weinrich, G.F.; Thompson, M.J.; Svoboda, J.A.
    Ecdysone oxidase and 3-oxoecdysteroid reductases in Manduca sexta midgut: kinetic parameters (1989), Arch. Insect Biochem. Physiol., 12, 201-218.
No PubMed abstract available

Inhibitors

Inhibitors Comment Organism Structure
methanol
-
Manduca sexta

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.013
-
ecdysone
-
Manduca sexta

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm
-
Manduca sexta 5737
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
20-hydroxyecdysone + O2 Manduca sexta first step in reaction sequence for the conversion of ecdysone and 20-hydroxyecdysone to their 3(alpha)-epimers 3-dehydro-20-hydroxyecdysone + H2O2
-
?
ecdysone + O2 Manduca sexta first step in reaction sequence for the conversion of ecdysone and 20-hydroxyecdysone to their 3(alpha)-epimers 3-dehydroecdysone + H2O2
-
?

Organism

Organism UniProt Comment Textmining
Manduca sexta
-
tobacco hornworm
-

Purification (Commentary)

Purification (Comment) Organism
partial Manduca sexta

Source Tissue

Source Tissue Comment Organism Textmining
larva
-
Manduca sexta
-
midgut
-
Manduca sexta
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
20-hydroxyecdysone + O2
-
Manduca sexta 3-dehydro-20-hydroxyecdysone + H2O2
-
?
20-hydroxyecdysone + O2 first step in reaction sequence for the conversion of ecdysone and 20-hydroxyecdysone to their 3(alpha)-epimers Manduca sexta 3-dehydro-20-hydroxyecdysone + H2O2
-
?
ecdysone + O2
-
Manduca sexta 3-dehydroecdysone + H2O2
-
?
ecdysone + O2 first step in reaction sequence for the conversion of ecdysone and 20-hydroxyecdysone to their 3(alpha)-epimers Manduca sexta 3-dehydroecdysone + H2O2
-
?