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Literature summary for 1.1.3.12 extracted from

  • Wongnate, T.; Chaiyen, P.
    The substrate oxidation mechanism of pyranose 2-oxidase and other related enzymes in the glucose-methanol-choline superfamily (2013), FEBS J., 280, 3009-3027.
    View publication on PubMed

Protein Variants

Protein Variants Comment Organism
H460A/H462A inactive Pseudomonas sp. MA-1

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
54000
-
1 * 54000, SDS-PAGE Microbacterium luteolum
55000
-
1 * 55000, SDS-PAGE Mesorhizobium loti

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
pyridoxine + O2 Mesorhizobium loti
-
pyridoxal + H2O2
-
?
pyridoxine + O2 Microbacterium luteolum
-
pyridoxal + H2O2
-
?
pyridoxine + O2 Pseudomonas sp. MA-1
-
pyridoxal + H2O2
-
?

Organism

Organism UniProt Comment Textmining
Mesorhizobium loti
-
-
-
Microbacterium luteolum
-
-
-
Pseudomonas sp. MA-1
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information 2,6-dihydroxypridine, 3-pyridinemethanol, and 4-pyridinemethanol give about 0.15% of the activity as compared with pyridoxine. The enzyme cannot use pyridoxal 5'-phosphate as a substrate Microbacterium luteolum ?
-
?
additional information 2,6-dihydroxypridine, 3-pyridinemethanol, and 4-pyridinemethanol give about 0.15% of the activity as compared with pyridoxine. The enzyme cannot use pyridoxal 5'-phosphate as a substrate Pseudomonas sp. MA-1 ?
-
?
additional information 2,6-dihydroxypridine, 3-pyridinemethanol, and 4-pyridinemethanol give only about 0.15% of the activity as compared with pyridoxine. The enzyme cannot use pyridoxal 5'-phosphate as a substrate Mesorhizobium loti ?
-
?
pyridoxine + O2
-
Mesorhizobium loti pyridoxal + H2O2
-
?
pyridoxine + O2
-
Microbacterium luteolum pyridoxal + H2O2
-
?
pyridoxine + O2
-
Pseudomonas sp. MA-1 pyridoxal + H2O2
-
?

Subunits

Subunits Comment Organism
monomer 1 * 54000, SDS-PAGE Microbacterium luteolum
monomer 1 * 55000, SDS-PAGE Mesorhizobium loti

Synonyms

Synonyms Comment Organism
PNO
-
Mesorhizobium loti
PNO
-
Microbacterium luteolum
PNO
-
Pseudomonas sp. MA-1

Cofactor

Cofactor Comment Organism Structure
FAD
-
Mesorhizobium loti
FAD
-
Microbacterium luteolum
FAD
-
Pseudomonas sp. MA-1

General Information

General Information Comment Organism
metabolism first enzyme in the vitamin B6 degradation pathway Mesorhizobium loti
metabolism first enzyme in the vitamin B6 degradation pathway Microbacterium luteolum
metabolism first enzyme in the vitamin B6 degradation pathway Pseudomonas sp. MA-1